参考文献 References
[1] Kirchner S,Ignatova Z.Emerging roles of tRNA in adaptive translation, signalling dynamics and disease[J]. Nat RevGenet, 2014,16(2):98-112.
[2] Torres AG, Batlle E, Ribas de Pouplana L.Role of tRNA modifications in human diseases[J].Trends Mol Med, 2014.20(6):306-314.
[3] Luo Y, Yao Y, Wu P, et al. The potential role of N7-methylguanosine (m7G) in cancer[J]. J Hematol Oncol, 2022. 15(1):63.
[4] Mathias S, Carsten H, Melissa B, et al. Compilation of tRNA sequences and sequences of tRNA genes[J]. Nucleic Acids Research, 1998(1):148-153.
[5] Phizicky EM, Alfonzo JD. Do all modifications benefit all tRNAs? [J].FEBS Lett, 2010.584(2):265-71.
[6] Jovine L, Djordjevic S, Rhodes D. The crystal structure of yeast phenylalanine tRNA at 2.0 A resolution: cleavage by Mg(2+) in 15-year old crystals[J].J Mol Biol, 2000.301(2):401-414.
[7] Zhang LS, Liu C, Ma H, et al.Transcriptome-wide Mapping of Internal N(7)-Methylguanosine Methylome in Mammalian mRNA[J]. Mol Cell, 2019.74(6): 1304- 1316.e8.
[8] Lin S, Liu Q, Lelyveld VS,et al.Mettl1/Wdr4-Mediated m(7)G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation[J]. Mol Cell, 2018. 71(2):244-255.e5.
[9] Ma J, Zhang L, Chen J,et al.m(7)GDisAI: N7- methylguanosine (m(7)G) sites and diseases associations inference based on heterogeneous network[J]. BMC Bioinformatics, 2021. 22(1): 152.
[10] Malbec L,Zhang T, Chen YS, et al.Dynamic methylome of internal mRNA N(7)-methylguanosine and its regulatory role in translation[J]. Cell Res, 2019.29(11): 927-941.
[11] Chen Z, Zhu W, Zhu S, et al.METTL1 promotes hepatocarcinogenesis via m(7) G tRNA modification- dependent translation control[J]. Clin Transl Med, 2021.11(12): e661.
[12] Deng Y, Zhou Z, Lin S,et al.METTL1 limits differentiation and functioning of EPCs derived from human-induced pluripotent stem cells through a MAPK/ ERK pathway[J]. Biochem Biophys Res Commun, 2020. 527(3): 791-798.
[13] Irie HY, Pearline RV, Grueneberg D, et al.Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition[J]. J Cell Biol, 2005.171(6):1023-1034.
[14] Cartlidge RA, Knebel A, Peggie M,et al.The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells[J]. Embo j, 2005.24(9):1696-1705.
[15] Balzeau J, Menezes MR, Cao S,et al.The LIN28/let-7 Pathway in Cancer[J]. Front Genet,2017.8:31.
[16] Liu Y, Zhang Y, Chi Q,et al. Methyltransferase-like 1 (METTL1) served as a tumor suppressor in colon cancer by activating 7-methyguanosine (m7G) regulated let-7e miRNA/HMGA2 axis[J]. Life Sci, 2020.249:117480.
[17] De Paolis V, Lorefice E, Orecchini E,et al.Epitranscriptomics: A New Layer of microRNA Regulation in Cancer[J]. Cancers, 2021.13(13):3372.
[18] Lehmann SM, Krüger C, Park B, et al.An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration[J]. Nat Neurosci, 2012.15(6): 827-35.
[19] McDaniel K, Hall C, Sato K, et al. Lin28 and let-7: roles and regulation in liver diseases[J]. Am J Physiol Gastrointest Liver Physiol, 2016.310(10):G757-765.
[20] Shyh-Chang N, Zhu H, Yvanka de Soysa T,et al.Lin28 enhances tissue repair by reprogramming cellular metabolism[J]. Cell, 2013.155(4):778-792.
[21] Visvanathan A, Patil V, Arora A,et al. Essential role of METTL3-mediated m(6)A modification in glioma stem-like cells maintenance and radioresistance[J]. Oncogene, 2018.37(4):522-533.
[22] Liu Y, Yang C, Zhao Y,et al. Overexpressed methyltransferase-like 1 (METTL1) increased chemosensitivity of colon cancer cells to cisplatin by regulating miR-149-3p/S100A4/p53 axis[J]. Aging (Albany NY), 2019.11(24):12328-12344.
[23] He M, Zheng B, Zhang Y, et al. KLF4 mediates the link between TGF-β1-induced gene transcription and H3 acetylation in vascular smooth muscle cells[J]. Faseb j, 2015.29(9): 4059-4070.
[24] Tian QH, Zhang MF, Zeng JS,et al.METTL1 overexpression is correlated with poor prognosis and promotes hepatocellular carcinoma via PTEN[J]. J Mol Med (Berl), 2019. 97(11): 1535-1545.
[25] Ji JW, Zhang YD, Lai YJ, et al.Mettl3 regulates the proliferation, migration and invasion of glioma cells by inhibiting PI3K/Akt signaling pathway[J]. Eur Rev Med Pharmacol Sci, 2020. 24(7):3818-3828.
[26] Li L, Yang Y, Wang Z, Xu C,et al.Prognostic role of METTL1 in glioma[J]. Cancer Cell Int, 2021. 21(1):633.
[27] Pandolfini L, Barbieri I, Bannister AJ, et al.METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation[J]. Mol Cell, 2019.74(6):1278-1290.e9.
[28] Barbieri I, Kouzarides T. Role of RNA modifications in cancer[J]. Nat Rev Cancer, 2020.20(6):303-322.
[29] Orellana EA, Liu Q, Yankova E,et al.METTL1-mediated m(7)G modification of Arg-TCT tRNA drives oncogenic transformation[J]. Mol Cell, 2021.81(16):3323-3338.e14.
[30] Dai Z, Liu H, Liao J, et al.N(7)-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression[J]. Mol Cell, 2021.81(16):3339-3355.e8.
[31] Ma J, Han H, Huang Y,et al.METTL1/WDR4-mediated m(7)G tRNA modifications and m(7)G codon usage promote mRNA translation and lung cancer progression[J]. Mol Ther, 2021.29(12):3422-3435.
[32] Han H, Yang C, Ma J, et al.N(7)-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ ULK1/ autophagy axis[J]. Nature communications, 2022.13(1): 1478-1478.
[33] Ying X, Liu B, Yuan Z, et al.METTL1-m(7) G-EGFR/ EFEMP1 axis promotes the bladder cancer development[J]. Clin Transl Med, 2021.11(12):e675.
[34] Orellana EA, Liu Q, Yankova E, et al.METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation[J]. Molecular Cell, 2021.81 (16): 3323-3338.e14.