Endoscopic submucosal dissection for early gastric cancer and precancerous lesions
内镜黏膜下剥离术治疗早期胃癌及癌前病变的疗效分析

摘要

目的 分析内镜黏膜下剥离术治疗早期胃癌及癌前病变的疗效。方法 选择我院于2019.10-2021.10月，2年内收治的110例早期胃癌及癌前病变患者，将所有患者随机分组为对照组（55例，采用传统根治性切除手术治疗）和治疗组（55例，实施内镜黏膜下剥离术治疗），观察两组手术时间、术中出血量、住院时间、术后并发症发生率以及肿瘤完整切除率。结果治疗组手术时间、术中出血量、住院时间、术后并发症发生率均明显低于对照组，差异均有统计学意义（P＜0.05），治疗组肿瘤完整切除率略高于对照组，差异无统计学意义（P＞0.05）。结论 内镜黏膜下剥离术治疗早期胃癌及癌前病变疗效理想，可显著减少术中出血量，缩短手术时间和住院时间，降低术后并发症发生率，有较高应用价值。

Abstract

Objective: To analyze the efficacy of endoscopic submucosal dissection in the treatment of early gastric cancer and precancerous lesions.
Methods: 110 patients with early gastric cancer and precancerous lesions treated in our hospital from October 2019 to October 2021 were randomly divided into control group (55 cases, treated with traditional radical resection) and treatment group (55 cases, treated with endoscopic submucosal dissection),the operation time, intraoperative bleeding, hospitalization time, postoperative complication rate and complete tumor resection rate were observed in the two groups.
Results: the operation time, intraoperative bleeding, hospital stay and postoperative complication rate in the treatment group were significantly lower than those in the control group (P < 0.05). The complete tumor resection rate in the treatment group was slightly higher than that in the control group (P > 0.05).
Conclusion  : endoscopic submucosal dissection is effective in the treatment of early gastric cancer and precancerous lesions. It can significantly reduce the amount of intraoperative bleeding, shorten the operation time and hospital stay, and reduce the incidence of postoperative complications.