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当前位置：国际临床研究杂志 > 2022年 6卷 (6)期

Open Access Article

International Journal of Clinical Research. 2022; 6: (6) ; 20-23 ; DOI: 10.12208/j.ijcr.20220248.

Correlation Analysis Between Gallstone and CA 199
胆囊结石与CA 199指标相关性分析

作者： 罗彪, 何丹 *, 黄韬, 曹茜

四川大学华西医院西藏成办分院普外科四川成都

*通讯作者：何丹,单位：四川大学华西医院西藏成办分院普外科四川成都；

四川省科技厅重点研发项目：2019YFS0372

发布时间: 2022-08-12 总浏览量: 722

PDF 全文下载引用本文收录截图（CNKI-Scholar）万方数据（WANFANG DATA）

摘要

目的探讨CA 199增高与胆囊结石并发胆囊癌的相关性。方法收集我院2010年1月-2020年6月收治的2314名胆囊结石患者，将胆囊结石患者分为平诊组和急诊组两组进行CA 199结果统计分析。结果两组患者CA 199增高阳性率比较差异有统计学意义（P<0.05），急诊组CA 199阳性率高。Ca19-9增高两组患者胆囊癌患病率比较，胆囊癌患病率差异无统计学意义（P＞0.05）；两组患者胆囊癌患病率比较差异无统计学意义（P＞0.05）。结论平诊组和急诊组胆囊结石患者合并胆囊癌几率相当，急性炎症发作会导致Ca19-9增高，因此，在胆囊结石伴慢性胆囊炎急性发作的Ca19-9增高患者，诊断胆囊癌应慎重。

关键词： CA 199；胆囊结石；胆囊癌

Abstract

Objective to investigate the correlation between the increase of Ca 199 and gallstone complicated with gallbladder cancer.
Methods 2314 patients with cholecystolithiasis in our hospital from January 2010 to June 2020 were collected and divided into two groups: the flat diagnosis group and the emergency group.
Results The positive rate of CA 199 in the emergency group was higher than that in the control group (P < 0.05). There was no significant difference in the prevalence of gallbladder cancer between the two groups (P > 0.05); there was no significant difference in the prevalence of gallbladder cancer between the two groups (P > 0.05).
Conclusion The incidence of cholecystolithiasis combined with gallbladder cancer is similar between the two groups. Acute inflammation attack will lead to the increase of CA199. Therefore, in patients with cholecystolithiasis combined with acute attack of chronic cholecystitis, the diagnosis of gallbladder cancer should be cautious.

Key words： CA 199; Gallstone; Gallbladder Cance

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