Open Access Article
International Journal of Clinical Research. 2022; 6: (5) ; 57-59 ; DOI: 10.12208/j.ijcr.20220209.
Correlation between vaginal microecological factors and persistent HR-HPV infection
阴道微生态因子与HR-HPV持续感染的相关性研究
作者：
赵晓化,
李维艳 *,
秦天华,
吾力也提•艾比布拉
乌鲁木齐市妇幼保健院 新疆乌鲁木齐
*通讯作者：
李维艳,单位：乌鲁木齐市妇幼保健院 新疆乌鲁木齐；
发布时间: 2022-07-16 总浏览量: 335
PDF 全文下载
引用本文
万方数据（WANFANG DATA）
摘要
目的 针对阴道微生态因子与HR-HPV持续感染的相关性开展深入分析。方法 选择我院2019年12月到2020年12月826例妇科检查者为研究对象，收集其阴道微生物检测结果以及HR-HPV检测结果。结果 HR-HPV阳性组中乳酸杆菌含量偏多情况占比明显低于HR-HPV阴性组的占比，阴道清洁度3~4度明显高于HR-HPV阴性组，白细胞醋酶感染阳性明显高于HR-HPV阴性组，加德纳菌感染明显高于HR-HPV阴性组，组间差异具有统计学意义（P<0.05）。结论 阴道微生态因子与HR-HPV持续感染存在相关性。
关键词： 阴道微生态因子；乳酸杆菌；HR-HPV；持续感染；相关性
Abstract
Objective: To conduct an in-depth analysis of the correlation between vaginal microecological factors and persistent HR-HPV infection. Methods: From December 2019 to December 2020, 826 gynecological examiners in our hospital were selected as the research subjects, and their vaginal microbiological test results and HR-HPV test results were collected. Results: The proportion of high lactobacillus content in the HR-HPV positive group was significantly lower than that in the HR-HPV negative group, the vaginal cleanliness degree was significantly higher than that in the HR-HPV negative group, and the positive leukocyte acetase infection was significantly higher than that in the HR-HPV negative group. Higher than HR-HPV negative group, Gardnerella infection was significantly higher than HR-HPV negative group, the difference between groups was statistically significant (P<0.05). Conclusion : Vaginal microecological factors are associated with persistent HR-HPV infection.
Key words： vaginal microecological factors; lactobacillus; HR-HPV; persistent infection; correlation
参考文献 References
[1] 谢丽芬,黄健妹.止痒灵坐浴对湿热下注型LSIL伴HR-HPV感染女性阴道微生态及HR-HPV转归的影响[J].中国医药指南,2021,19(33):4-6. DOI:10.15912/j.cnki.gocm.2021.33.002.
[2] 陈文娟,杨晗,肖芬球.宫颈冷刀锥切术后HR-HPV持续感染与阴道微生态环境的相关性分析[J].中外医学研究,2021,19(06):7-10. DOI:10.14033/j.cnki.cfmr.2021.06.003.
[3] 叶丹萍.阴道微生态失衡、宫颈局部细胞因子变化与宫颈高危型HPV持续感染的相关性研究[J].实用妇科内分泌电子杂志,2020,7(14):41-42. DOI:10.16484/j.cnki.issn2095-8803.2020.14.028.
[4] 尹清,孟凡玉,缪志海.宫颈癌前病变合并HPV感染者炎症因子及阴道微生态环境分析[J].浙江实用医学,2019, 24(02):123-125. DOI:10.16794/j.cnki.cn33-1207/r.2019.02.015.
[5] 曾月,陈梦捷,覃露,等.体液免疫水平与宫颈上皮内病变及早期宫颈癌的相关性[J].2018,(12).
[6] 周旭,金洋,贾荣霞,等 阴道微生态在人乳头瘤病毒导致宫颈癌发生机制中的研究进展 . 中国老年学杂志, 2020 ,40 (14) :3122-3126
[7] 冯川萍 宫颈锥形切除术与根治性宫颈切除术治疗早期宫颈癌的效果比较 . 深圳中西医结合杂志, 2021 ,31 (4) :132-134
[8] 沈彩糯,王巧亚,洪威阳,等 阴道微生态改变与高危人乳头瘤病毒感染的关系研究 . 现代实用医学, 2021 ,33 (12) :1662-1664
引用本文
赵晓化, 李维艳, 秦天华, 吾力也提•艾比布拉, 阴道微生态因子与HR-HPV持续感染的相关性研究[J]. 国际临床研究杂志, 2022; 6: (5) : 57-59.