CSCIED

期刊目次

加入编委

期刊订阅

添加您的邮件地址以接收即将发行期刊数据:

Open Access Article

International Journal of Clinical Research. 2022; 6: (2) ; 152-155 ; DOI: 10.12208/j.ijcr.20220079.

Clinical effect of somatostatin combined with endoscopy in the treatment of esophagogastric variceal bleeding in patients with liver cirrhosis
生长抑素联合内镜治疗肝硬化食管胃底静脉曲张破裂出血的临床效果

作者: 董凤良 *

义乌天祥医疗东方医院 浙江义乌

*通讯作者: 董凤良,单位:义乌天祥医疗东方医院 浙江义乌;

发布时间: 2022-04-26 总浏览量: 517

摘要

目的 对于肝硬化食管胃底静脉曲张破裂出血患者采取生长抑素联合内镜进行治疗,进一步提高临床治疗效果,改善患者的临床多项症状,预防再次出血的风险。方法 2021年2月到2022年1月作为本次研究时间,选择我院接收的63例肝硬化食管胃底静脉曲张破裂出血患者作为本次研究对象来源,对照组接受生长抑素进行治疗,观察组接受生长抑素联合内镜进行治疗,比较两组治疗关键指标、再次出血率与止血成功率、并发症发生率。结果 观察组两组间关键指标对比比较有明显差异存在,观察组效果更好,此外,在止血成功率均高于对照组,再次出血率低于对照组(P<0.05),两组间并发症比较相近(P>0.05)。结论 在治疗肝硬化食管胃底静脉曲张破裂出血疾病中,通过采取生长抑素联合内镜进行治疗,取得了令人满意的效果,对患者出血症状有显著的改善效果,安全有效,值得推荐。

关键词: 生长抑素;内镜治疗;肝硬化;食管胃底静脉曲张破裂出血

Abstract

Objective: To treat patients with cirrhosis with esophagogastric varices bleeding by somatostatin combined with endoscopy to further improve the clinical treatment effect, improve the clinical symptoms of patients, and prevent the risk of rebleeding.
Methods: From February 2021 to January 2022 as the study time, 63 patients with liver cirrhosis with esophageal and gastric variceal bleeding received in our hospital were selected as the source of this study. The control group received somatostatin for treatment. The observation group received somatostatin combined with endoscopy for treatment, and the key indicators of treatment, rebleeding rate, hemostasis success rate, and complication rate were compared between the two groups.
Results: There were significant differences in the comparison of key indicators between the two groups in the observation group, and the effect in the observation group was better. In addition, the success rate of hemostasis was higher than that of the control group, and the rate of re-bleeding was lower than that of the control group (P<0.05). The complications were similar (P>0.05).
Conclusion  : In the treatment of liver cirrhosis esophagus and gastric variceal bleeding, the combination of somatostatin and endoscopy has achieved satisfactory results, and has significantly improved the bleeding symptoms of patients. It is safe and effective, and is worthy of recommendation.

Key words: Somatostatin; Endoscopic Therapy; Liver Cirrhosis; Esophagogastric Varices Bleeding

参考文献 References

[1] 易省阳,邹姣玲,王翔,等.不同剂量生长抑素治疗肝硬化合并食管胃底静脉曲张破裂出血的临床效果研究[J].中国全科医学,2017,20(19):2363-2368.

[2] 丹珠永吉,刘芝兰,禄艳艳,等.内镜下序贯套扎和硬化剂治疗肝硬化并发食管胃底静脉曲张破裂出血患者疗效及对血流动力学的影响对比研究[J].实用肝脏病杂志,2019,22(5):692-695.

[3] 从伟成,朱叶珊,高伟,等.内镜联合生长抑素治疗肝硬化合并食管胃底静脉曲张破裂出血的疗效研究[J].肝脏,2017,22(2):149-151.

[4] 高山,王玮,童旭东,等.内镜介入联合药物治疗肝硬化食管胃底静脉曲张破裂出血的疗效观察[J].临床内科杂志,2019,36(10):710-711.

[5] 樊超,郑集家,高子昭,等.内镜下治疗气管插管患者肝硬化胃底静脉曲张破裂出血1例报道[J].现代消化及介入诊疗,2019,24(7):815-817.

[6] 中华医学会外科学分会脾及门静脉高压外科学组.肝硬化门静脉高压症食管、胃底静脉曲张破裂出血诊治专家共识(2019版)[J].中华外科杂志,2019,57(12): 885-892.

[7] 易省阳,邹姣玲,王翔,等.加倍剂量生长抑素治疗肝硬化食管胃底静脉曲张破裂出血疗效观察[J].中华实用诊断与治疗杂志,2017,31(9):917-919.

[8] 何晓燕,胡建文,吕响银,等.内镜下套扎术及硬化剂注射术同步和序贯治疗食管静脉曲张的随机对照研究[J].浙江医学,2019,41(8):813-816.

[9] 韩文,马鹏,戴光荣,等.内镜联合药物治疗方案对急性食管胃静脉曲张出血患者临床疗效的影响[J].中国中西医结合急救杂志,2019,26(4):433-435.

[10] 史增辉,代金玉,苏卫仙.生长抑素对肝硬化食管胃底静脉曲张破裂出血患者血流动力学指标及胃肠激素水平的影响[J].临床误诊误治,2019,32(2):31-35.

引用本文

董凤良, 生长抑素联合内镜治疗肝硬化食管胃底静脉曲张破裂出血的临床效果[J]. 国际临床研究杂志, 2022; 6: (2) : 152-155.