摘要
目的 回顾性有序Logistic 回归分析围产期相关因素，探索新生儿窒息主要危险因素，预防和减少新生儿窒息。方法 新生儿根据出生时Apgar 评分将分为正常、轻度窒息、重度窒息。围产期相关因素为自变量。回顾性有序Logistic 回归分析新生儿窒息围产期相关危险因素。结果 ①羊水Ⅰ度混浊和羊水Ⅲ度混浊能增加新生儿窒息风险（p＜0.05)，OR值分别是9.42和9.84，OR 95%CI分别是(2.83~31.39)和(2.40~40.26)，有统计学意义。②身长小于及等于45cm新生儿相对于身长≥51cm新生儿窒息发生高（p＜0.05)，OR值分别是25.33和38.32，95%CI（1.32~484.81）和（3.93~373.72），有统计学意义。③出生缺陷也能增加新生儿窒息发生风险（p＜0.05)，OR值38.40，95%CI（8.69~169.64），有统计学意义。结论 孕期贫血、羊水混浊、出生缺陷以及新生儿身长偏小能增加新生儿窒息风险。
关键词： 新生儿窒息；围产期相关因素；新生儿Apgar评分；Ordinal Logistic回归分析
Abstract
Objective: To retrospectively ordinal Logistic regression analyze perinatal related factors, explore the main risk factors of neonatal asphyxia, prevent and reduce neonatal asphyxia. Methods: According to Apgar score at birth, These neonates was divided into normal, mild asphyxia and severe asphyxia. Perinatal related factors were as independent variables. Perinatal neonatal asphyxia related dangerous factors were retrospective ordinal Logistic regression analyzed. Results: ①Ⅰdegree amniotic fluid turbidity and Ⅲ degree amniotic fluid turbidity could respectively increase the risk of neonatal asphyxia, their OR values were 9.42 and 9.84, 95% CI(2.83~31.39) and (2.40~40.26) . their p value less than 0.05. Difference was statistical significance.②The incidence of neonatal asphyxia with body length less 46cm were higher than in neonates which body length was more than or equal to 51 cm (p < 0.05). OR value were respectively 25.33 and 38.32. 95% CI were (1.32~484.81) and (3.93~373.72). These was statistically significant.③Noenatal birth defects could also increase the occurrence risk of neonatal asphyxia (p<0.05). OR value was 38.40,95%CI(8.69~169.64), which was statistically significant. Conclusion : Pregnancy anemia, amniotic fluid turbidity, birth defects and small neonatal length could increase the incident risk of neonatal asphyxia.
Key words： Neonatal Asphyxia, Perinatal Related factors, Neonatal Apgar scores, Ordinal Logistic Regression Analysis
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