Observation of curative effect of anti-infective drugs and comprehensive measures on reducing perioperative infection in gynecology and obstetrics before operation
术前预防应用抗感染药物及综合措施对降低妇产科围手术期感染的疗效观察

摘要

目的：研究术前预防应用抗感染药物及综合措施对降低妇产科围手术期感染的临床使用效果。方法：选取我院2019年2月~2019年8月期间收治的需要进行妇产科手术的患者作为此次研究对象，共计88例。需要研究人员将该部分患者按照摸球法分为对照组(44例)与观察组（44例），对照组妇产科患者术后运用抗感染药物与常规治疗方式，而观察组妇产科患者术前采用抗感染药物与综合治疗方式，研究期间需要护理人员做好记录工作，对比两组患者治疗有效率、C-反应蛋白、降钙素原、切口感染、产褥感染以及住院时间等。结果：观察组妇产科手术患者术前采用抗感染药物与综合治疗后治疗有效率为93.2%，而对照组妇产科手术患者运用术后抗感染与常规治疗方式治疗有效率为86.4%，观察组数据明显优于对照组，组间差异显著（P＜0.05）。此外，观察组妇产科患者术后C-反应蛋白（2.62±0.72）ml/L、降钙素原（2.83±0.84）ng/ml，相较于对照组妇产科患者术后C-反应蛋白（4.21±1.42）ml/L、降钙素原（5.87±1.32）ng/ml低，数据对比有差异，具有统计学意义（P＜0.05）。结论：针对妇产科手术患者术前运用抗感染药物与综合治疗，可以有效提高治疗有效率，降低切口感染率，值得临床推广使用。

Abstract

Objective: To study the clinical effects of preoperative prevention of anti-infective drugs and comprehensive measures on reducing perioperative infection in gynecology and obstetrics.
Methods: A total of 88 patients who were admitted to our hospital from February 2019 to August 2019 and required gynecological and obstetric surgery were selected as the subjects of this study. Researchers are required to divide these patients into the control group (44 cases) and the observation group (44 cases) according to the touch method. The control group of patients with obstetrics and gynecology uses anti-infective drugs and conventional treatment methods, and the observation group of obstetrics and gynecology Patients were treated with anti-infective drugs and comprehensive treatment before surgery. Nursing staff were needed to keep records during the study period. The treatment efficiency, C-reactive protein, procalcitonin, incision infection, puerperal infection, and length of hospital stay were compared between the two groups.
Results: Observation group patients with gynecological and obstetric surgery received anti-infective drugs and comprehensive treatment after treatment with an effective rate of 93.2%, while control group patients with postoperative anti-infection and conventional treatment with an effective rate of 86.4%. The data in the observation group were significantly better than those in the control group, with significant differences between the groups (P <0.05). In addition, the postoperative C-reactive protein (2.62 ± 0.72) ml / L and procalcitonin (2.83 ± 0.84) ng / ml in the observation group of gynecological and obstetric patients were compared with the postoperative C-response of the gynecological and obstetric patients in the control group. The protein (4.21 ± 1.42) ml / L and procalcitonin (5.87 ± 1.32) ng / ml were low. The data comparison was different and had statistical significance (P <0.05).
Conclusion  : The application of anti-infective drugs and comprehensive treatment for gynecological and obstetric surgery patients before surgery can effectively improve the treatment efficiency and reduce the rate of incision infection, which is worthy of clinical popularization.