Exploration of clinical application of He-Ne laser irradiation, local injection of triamcinolone acetonide combined with oral administration of tranilast in the treatment of keloids
氦氖激光照射,曲安奈德局部注射联合口服曲尼司特治疗瘢痕疙瘩临床应用探讨

摘要

目的 针对瘢痕疙瘩，采用氦氖激光照射、曲安奈德局部注射与口服曲尼司特联合干预，评估其临床疗效。方法 采用回顾性分析，选择2024年1月至2025年12月收治的瘢痕疙瘩患者资料60例作为研究对象，将其按照治疗方案的不同分为对照组（n=30例，单纯曲安奈德局部注射联合口服曲尼司特）与观察组（n=30例，在对照组基础上予以氦氖激光照射治疗）。对比两组治疗效果。结果 观察组症状改善情况、瘢痕修复情况均优于对照组，焦虑、抑郁自评量表（SAS、SDS）评分均低于对照组（P<0.05）。结论 在瘢痕疙瘩的治疗中，联合应用氦氖激光照射、曲安奈德局部注射与口服曲尼司特，能够使临床疗效获得显著提升，改善瘢痕外观及症状，促进康复。

Abstract

Objective For keloids, a combined intervention of helium-neon laser irradiation, local triamcinolone acetonide injection, and oral tranilast was employed to evaluate its clinical efficacy.
Methods A retrospective analysis was conducted on 60 patients with keloid treated from January 2024 to December 2025 as the study subjects. They were divided into a control group (n=30, treated with local injection of triamcinolone acetonide combined with oral administration of tranilast) and an observation group (n=30, treated with helium neon laser irradiation on the basis of the control group) according to different treatment plans. Compare the therapeutic effects of two groups.
Results The improvement of symptoms and scar repair in the observation group were better than those in the control group, and the Self‑Rating Anxiety Scale and Self‑Rating Depression Scale (SAS, SDS) scores were lower than those in the control group (P<0.05).
Conclusion   In the treatment of keloids, the combined application of helium-neon laser irradiation, local injection of triamcinolone acetonide, and oral tranilast can significantly enhance clinical efficacy, improve scar appearance and symptoms, and promote recovery.