摘要
目的 考察联合吸入布地奈德和特布他林对急性发作期慢阻肺病人的临床改善情况。方法 将2024年5月至2025年6月就诊的74例急性加重期慢阻肺患者作为前瞻性分析对象,通过数字表随机抽样均分2组,对照组(37例)进行常规治疗,观察组(37例)则进行布地奈德+特布他林治疗。对患者整体治疗效果以及症状改善用时统计。结果 整体治疗有效率方面,观察组高于对照组(P<0.05)。与对照组相比,观察组各症状的改善耗时更少(P<0.05)。结论 对于慢性阻塞性肺疾病急性加重期病例,联合使用布地奈德和特布他林进行治疗,能够促使患者的临床症状在较短时间内得到有效改善,提升临床治疗有效率,起到帮助患者进行恢复的作用。
关键词: 布地奈德;特布他林;急性加重期慢性阻塞性肺疾病
Abstract
Objective Investigating the clinical improvement of combined inhalation of budesonide and terbutaline in patients with acute exacerbation of chronic obstructive pulmonary disease. Methods A prospective analysis was conducted on 74 patients with acute exacerbation of chronic obstructive pulmonary disease who were treated from May 2024 to June 2025. The patients were randomly divided into two groups using a digital table. The control group (37 cases) received conventional treatment, while the observation group (37 cases) received treatment with budesonide and terbutaline. Statistics on the overall treatment effect and symptom improvement time of patients. Results In terms of overall treatment efficacy, the observation group was higher than the control group, (P<0.05). Compared with the control group, the observation group took less time to improve each symptom (P<0.05). Conclusion For cases of acute exacerbation of chronic obstructive pulmonary disease, the combined use of budesonide and terbutaline can effectively improve the clinical symptoms of patients in a short period of time, enhance the effectiveness of clinical treatment, and help patients recover.
Key words: Budesonide; Terbutaline; Acute exacerbation of chronic obstructive pulmonary disease
参考文献 References
[1] 胡竹秋,龙丰梅. 特布他林联合布地奈德对慢性阻塞性肺疾病急性加重期患者呼吸困难症状及肺功能的影响 [J]. 基层医学论坛, 2025, 29 (33): 78-80+84.
[2] 李文艳,许志强. 硫酸特布他林联合布地奈德治疗慢性阻塞性肺疾病急性加重期患者的效果 [J]. 中国民康医学, 2025, 37 (20): 46-49.
[3] 黄莉. 谷胱甘肽联合布地奈德、特布他林治疗慢性阻塞性肺疾病急性加重期患者的效果分析 [J]. 中国社区医师, 2025, 41 (22): 4-6.
[4] 世界中医药学会联合会内科专业委员会,李建生,余学庆.慢性阻塞性肺疾病中西医结合诊疗指南(2022版)[J].中国循证医学杂志, 2023, 23(10):1117-1128.
[5] 李德能. 特布他林联合布地奈德、异丙托溴铵治疗慢性阻塞性肺疾病急性加重期的临床效果分析 [J]. 中外医药研究, 2025, 4 (16): 31-33.
[6] 王丽,郝建霞. 糖皮质激素、特布他林、胰岛素联合治疗糖尿病合并慢性阻塞性肺疾病急性加重期的疗效 [J]. 糖尿病新世界, 2025, 28 (08): 84-87.
[7] 赵娜,马周旺,李玉梅. 布地奈德混悬液联合特布他林雾化治疗慢性阻塞性肺疾病急性加重期的效果及对嗜酸性粒细胞水平的影响 [J]. 中国药物经济学, 2025, 20 (03): 86-89+108.
[8] 林静. 糖皮质激素联合特布他林治疗慢性阻塞性肺疾病急性加重期的效果探讨 [J]. 中外医药研究, 2025, 4 (08): 45-47.
[9] 魏彬,贺兴全,文敏,等. 特布他林联合布地奈德用于慢性阻塞性肺疾病急性加重期患者的疗效及安全性观察 [J]. 大医生, 2025, 10 (05): 62-64.
[10] 陈秋印,吴敬梅,罗成. 布地奈德联合特布他林雾化对慢性阻塞性肺疾病急性加重期的治疗效果 [J]. 中外医疗, 2025, 44 (04): 72-76.