摘要
目的 探究循证医学指导下的综合护理联合阻力训练在肿瘤肌少症患者中的应用成效，为临床干预方案优化提供依据。方法 选取2023年1月-2024年6月本院收治的86例肿瘤肌少症患者为研究对象，采用随机数字表法分为实验组（43例）与对照组（43例）。对照组实施肿瘤肌少症常规护理，实验组在对照组基础上实施循证医学综合护理联合阻力训练，干预周期12周。比较两组干预前后肌少症相关指标、身体功能指标、营养状况指标及生活质量指标。结果 干预后，实验组骨骼肌质量指数（SMI）、握力、下肢肌肉力量均高于对照组（P<0.05）；实验组6min步行距离、起立-行走测试时间均优于对照组（P<0.05）；实验组血清白蛋白（ALB）、前白蛋白（PA）、血红蛋白（Hb）水平均高于对照组（P<0.05）。结论 循证医学综合护理结合阻力训练可有效改善肿瘤肌少症患者的肌肉含量与肌力，提升身体运动功能，优化营养状况，具有较高的临床应用价值。
关键词： 循证医学；综合护理；阻力训练；肿瘤肌少症；肌肉功能；生活质量
Abstract
Objective To explore the application effectiveness of comprehensive nursing combined with resistance training under the guidance of evidence-based medicine in patients with tumor myopathy, and provide a basis for optimizing clinical intervention plans. Methods 86 patients with tumor myopathy admitted to our hospital from January 2023 to June 2024 were selected as the research subjects. They were randomly divided into an experimental group (43 cases) and a control group (43 cases) using a random number table method. The control group received routine care for tumor muscular dystrophy, while the experimental group received evidence-based medicine comprehensive nursing combined with resistance training on the basis of the control group, with an intervention period of 12 weeks. Compare the muscle atrophy related indicators, physical function indicators, nutritional status indicators, and quality of life indicators between two groups before and after intervention. Results After intervention, the skeletal muscle mass index (SMI), grip strength, and lower limb muscle strength of the experimental group were all higher than those of the control group (P<0.05); The experimental group had a better 6-minute walking distance and standing walking test time than the control group (P<0.05); The levels of serum albumin (ALB), prealbumin (PA), and hemoglobin (Hb) in the experimental group were higher than those in the control group (P<0.05). Conclusion Evidence based comprehensive nursing combined with resistance training can effectively improve muscle mass and strength, enhance physical function, optimize nutritional status, and have high clinical application value in patients with tumor myopathy.
Key words： Evidence-based medicine; Comprehensive nursing; Resistance training; Tumor muscular dystrophy; Muscle function; Quality of life
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