Evaluation and analysis of the intervention effect of predictive nursing on chemotherapy-induced nausea and vomiting in cancer patients
预见性护理对肿瘤患者化疗所致恶心呕吐的干预效果评价分析

摘要

目的 探析预见性护理运用于肿瘤患者化疗中，对预防恶心呕吐的效果。方法 自2025年1月起，本院开始收集化疗治疗肿瘤患者的病例资料，至2026年1月止共纳入102例，通过随机数字表法平均分组。参照组开展常规护理；实验组开展预见性护理。比较两组不同时期恶心呕吐的控制率以及脑肠肽水平等情况。结果 实验组急性期、延迟期、全呕期恶心呕吐的控制率均较参照组显著偏高（P<0.05）。实验组P物质、5-羟色胺、胆囊收缩素水平均较参照显著偏高（P<0.05）；而胃动素水平较参照组显著偏低（P<0.05）。结论 预见性护理运用于肿瘤患者化疗中，可明显降低胃动素水平，有效控制不同时期的恶心呕吐，效果显著，应积极推广。

Abstract

Objective To explore the effectiveness of predictive nursing in preventing nausea and vomiting in cancer patients undergoing chemotherapy.
Methods Starting from January 2025, our hospital will begin collecting case data of cancer patients undergoing chemotherapy treatment. By January 2026, a total of 102 cases will be included and evenly divided through random number table method. Conduct routine nursing care in the reference group; The experimental group carried out predictive nursing. Compare the control rate of nausea and vomiting and the levels of brain gut peptides between two groups at different stages.
Results The control rate of nausea and vomiting in the acute phase, delayed phase, and total vomiting phase of the experimental group was significantly higher than that of the reference group (P<0.05). The levels of substance P, serotonin, and cholecystokinin in the experimental group were significantly higher than those in the reference group (P<0.05); The level of motilin was significantly lower than that of the reference group (P<0.05).
Conclusion   The application of anticipatory nursing in chemotherapy for cancer patients can significantly reduce the level of motilin, effectively control nausea and vomiting at different stages, and have significant effects. It should be actively promoted.