Clinical effect analysis of CO₂ fractional laser on facial skin photoaging
CO₂点阵激光治疗面部皮肤光老化临床效果分析

摘要

目的 探讨CO₂点阵激光治疗面部皮肤光老化的临床效果及安全性。方法 选取2024年6月至2025年6月在本院皮肤科就诊的80例面部皮肤光老化患者，按随机数字表法分为观察组与对照组，观察组采用CO₂点阵激光治疗，对照组采用常规外用药物联合强脉冲光治疗。比较两组皱纹改善总有效率、皮肤弹性恢复评分、色素沉着消退面积以及不良反应发生情况。结果 观察组皱纹改善总有效率、皮肤弹性恢复评分、色素沉着消退面积占比显著高于对照组；与对照组相比，观察组的不良反应发生率更低（P＜0.05）。结论 CO₂点阵激光治疗面部皮肤光老化效果显著，能有效改善皱纹、恢复皮肤弹性、消退色素沉着，且安全性较高，值得临床推广应用。

Abstract

Objective To investigate the clinical efficacy and safety of CO₂ fractional laser therapy for facial skin photoaging.
Methods A total of 80 patients with facial skin photoaging who visited the dermatology department of our hospital from June 2024 to June 2025 were selected and randomly divided into an observation group and a control group using a random number table. The observation group received CO₂ fractional laser therapy, while the control group received conventional topical medications combined with intense pulsed light (IPL) therapy. The total effective rate of wrinkle improvement, skin elasticity recovery score, area of pigment regression, and incidence of adverse reactions were compared between the two groups.
Results The observation group showed significantly higher rates of total effective wrinkle improvement, skin elasticity recovery score, and area of pigment regression compared to the control group. Additionally, the incidence of adverse reactions was lower in the observation group (P<0.05).
Conclusion   CO₂ fractional laser therapy demonstrates significant efficacy in treating facial skin photoaging, effectively improving wrinkles, restoring skin elasticity, and reducing pigmentation. It also exhibits high safety, making it worthy of clinical promotion and application.