The value of low-frequency combined with high-frequency ultrasound in the diagnosis of early liver cirrhosis in chronic hepatitis B
低频联合高频超声在慢性乙肝早期肝硬化诊断中的价值

摘要

目的 探讨低频联合高频超声在慢性乙肝（CHB）早期肝硬化中的诊断价值。方法 选取我院接诊的90例CHB患者（2024年7月至2025年7月），均行低频超声、高频超声单独及联合检查，以肝穿刺活检为金标准，分为肝硬化组（42例）和非肝硬化组（48例），比较三种检查方式的诊断效能及相关超声指标。结果 联合检查的灵敏度、特异度、准确度等诊断效能指标均显著高于两种超声单独检查（P＜0.05）；肝硬化组门静脉、脾静脉内径大于非肝硬化组，血流速度低于后者（P＜0.05）。结论 低频联合高频超声可互补优势，提高慢性乙肝早期肝硬化诊断准确性，是可靠的无创影像学方法。

Abstract

Objective To explore the diagnostic value of low-frequency combined with high-frequency ultrasound in early liver cirrhosis of chronic hepatitis B (CHB).
Methods A total of 90 CHB patients (from July 2024 to July 2025) admitted to our hospital were selected. All patients underwent low-frequency ultrasound, high-frequency ultrasound, and combined low-frequency and high-frequency ultrasound examinations. Liver biopsy was used as the gold standard, and the patients were divided into the liver cirrhosis group (42 cases) and the non-liver cirrhosis group (48 cases). The diagnostic efficacy and related ultrasound indicators of the three examination methods were compared.
Results The diagnostic efficacy indicators such as sensitivity, specificity, and accuracy of the combined examination were significantly higher than those of the two ultrasound examinations alone (P < 0.05); the diameters of the portal vein and splenic vein in the liver cirrhosis group were larger than those in the non-liver cirrhosis group, and the blood flow velocity was lower (P < 0.05).
Conclusion   Low-frequency combined with high-frequency ultrasound can complement each other's advantages, improve the accuracy of diagnosing early liver cirrhosis in CHB, and is a reliable non-invasive imaging method.