The effect of acupuncture combined with acupoint plaster application on clinical symptoms and inflammatory factor levels of patients with non-alcoholic fatty liver disease
针灸联合穴位敷贴对非酒精性脂肪肝患者临床症状及炎症因子水平的影响

摘要

目的 分析、探讨针灸联合穴位敷贴对非酒精性脂肪肝（NAFLD）患者临床症状及炎症因子水平的影响，期待能为临床研究提供理论与实践参照。方法 研究以对比方式表达，将2023年9月至2024年9月设定为研究开展期限，将82例NAFLD患者纳入研究作为分析主体，采用双色球分组法完成组间安排，每组归入41例（n=41），分别命名为参照组与研究组，各组执行不同的治疗干预计划，即参照组：行常规治疗干预方案，研究组：开展常规治疗的同时，增加针灸联合穴位敷贴治疗方案，最终收集整理临床资料和相关数据，以临床症状积分、肝功能指标、血脂水平、炎症因子、生活质量评分为观察指标，比对不同干预策略下的效果和差异。结果 统计分析后发现，研究组整体干预效果更加理想，患者在上述各项指标数值的体现上，均显优参照组，P值达＜0.05，值得探讨。结论 对于非酒精肝性脂肪肝患者而言，在其临床治疗方案的横向选择中，建议首选联合干预模式（常规治疗干预+针灸联合穴位敷贴），此种操作形式一方面能切实改善患者临床症状，降低炎症因子水平，同时还可极大促进肝功能恢复，应用价值显著，值得推广。

Abstract

Objective To analyze and explore the effects of acupuncture combined with acupoint application on clinical symptoms and inflammatory factor levels in patients with non-alcoholic fatty liver disease (NAFLD), aiming to provide theoretical and practical references for clinical research.
Methods The study was conducted through comparative analysis, with the period from September 2023 to September 2024 designated as the study duration. A total of 82 NAFLD patients were enrolled as the study subjects, and the patients were assigned to groups using a two-color ball grouping method, with 41 cases in each group (n=41). The groups were named the reference group and the study group, respectively. Different treatment intervention plans were implemented: the reference group received conventional treatment, while the study group received conventional treatment combined with acupuncture and acupoint application. Clinical data and related information were collected and analyzed, with clinical symptom scores, liver function indicators, lipid levels, inflammatory factors, and quality of life scores used as observation indicators to compare the effects and differences under different intervention strategies.
Results Statistical analysis revealed that the study group demonstrated significantly better overall intervention outcomes, with all indicators showing superior values compared to the reference group (P-value <0.05), warranting further discussion.
Conclusion   For patients with non-alcoholic fatty liver disease, the combined intervention model (conventional treatment + acupuncture combined with acupoint application) is recommended as the preferred clinical treatment option. This approach not only effectively improves clinical symptoms and reduces inflammatory factor levels but also significantly promotes liver function recovery, demonstrating significant clinical value and worthy of promotion.