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当前位置：国际临床研究杂志 > 2026年 10卷 (4)期

Open Access Article

International Journal of Clinical Research. 2026; 10: (4) ; 17-21 ; DOI: 10.12208/j.ijcr.20260174.

The association between peripheral arterial disease and plantar pressure in diabetes: A research update
糖尿病外周动脉疾病与足底压力的关系研究进展

作者： 朱恩芳 *, 崔灏灵, 段中平, 毛舰, 李文 *

大理大学临床医学院，云南省第三人民医院内分泌科云南大理

*通讯作者：朱恩芳,单位：大理大学临床医学院，云南省第三人民医院内分泌科云南大理; ；李文,单位：大理大学临床医学院，云南省第三人民医院内分泌科云南大理; ；

发布时间: 2026-04-28 总浏览量: 35

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摘要

糖尿病外周动脉疾病（PAD）是糖尿病常见的严重并发症之一，以下肢动脉粥样硬化性闭塞和循环障碍为主要特征，是糖尿病足溃疡的主要病因之一。此外，足底压力异常作为糖尿病足的独立危险因素，与PAD相互影响，协同增加糖尿病足的发生风险。本文系统阐述了糖尿病PAD与足底压力相关性的最新研究进展，探讨了二者在糖尿病足发生发展中的相互作用机制。结果表明，PAD导致的组织灌注减少、足底压力升高和异常分布共同构成了糖尿病足的病理基础。综合评估下肢动脉情况和足底压力可为糖尿病患者的风险分层、预防干预和个体化治疗提供重要依据、对降低糖尿病足溃疡和截肢风险具有重要意义。

关键词： 糖尿病；糖尿病足溃疡；外周动脉疾病；足底压力；踝肱指数

Abstract

Diabetic peripheral artery disease (PAD) is one of the common complications of diabetes mellitus, primarily characterized by atherosclerotic occlusion and circulatory impairment in the lower limb arteries. It is one of the main causes of diabetic foot ulcer. Abnormal plantar pressure, as an independent risk factor for diabetic foot ulcer, interacts with PAD, synergistically increasing the risk of diabetic foot ulcer. This review summarizes recent research advances on the correlation between PAD and plantar pressure in patients with diabetes mellitus, exploring the interactive mechanisms in the development of diabetic foot. Recent studies indicate that reduced tissue perfusion due to PAD, combined with elevated and abnormally distributed plantar pressure, collectively form the pathological basis for diabetic foot ulcers. Comprehensive assessment of both lower limb arterial status and plantar pressure provides crucial evidence for risk stratification, preventive interventions, and personalized treatment in diabetic PAD patients, which are significant implications for reducing the risk of diabetic foot ulcer and amputation.

Key words： Diabetes mellitus; Diabetic foot ulcer; Peripheral arterial disease; Plantar pressure; Ankle-brachial index

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引用本文

朱恩芳, 崔灏灵, 段中平, 毛舰, 李文, 糖尿病外周动脉疾病与足底压力的关系研究进展[J]. 国际临床研究杂志, 2026; 10: (4) : 17-21.

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