Open Access Article
International Journal of Clinical Research. 2026; 10: (1) ; 116-118 ; DOI: 10.12208/j.ijcr.20260032.
Study on the treatment of chronic obstructive pulmonary disease with cefoperazone sulbactam combined with ambroxol hydrochloride
头孢哌酮舒巴坦联合盐酸氨溴索治疗慢阻肺的研究
作者：
潘海元,
蒯银伟 *
无锡市新吴区新瑞医院 江苏无锡
*通讯作者：
蒯银伟,单位：无锡市新吴区新瑞医院 江苏无锡；
发布时间: 2026-01-29 总浏览量: 24
PDF 全文下载
引用本文
摘要
目的 探究慢阻肺采用头孢哌酮舒巴坦联合盐酸氨溴索治疗的价值。方法 选取本院收治的慢阻肺患者共96例，随机分为2组各48例。对照组采用头孢哌酮舒巴坦治疗，观察组采用头孢哌酮舒巴坦联合盐酸氨溴索治疗。对比2组疗效。结果 治疗后观察组FVC、FEV1与对照组比较均增加，CAT、mMRC得分与对照组比较均减少（P＜0.05）。结论 慢阻肺采用头孢哌酮舒巴坦联合盐酸氨溴索治疗效果更好。
关键词： 慢阻肺；头孢哌酮舒巴坦；盐酸氨溴索
Abstract
Objective To explore the value of cefoperazone sulbactam combined with ambroxol hydrochloride in the treatment of chronic obstructive pulmonary disease. Methods A total of 96 patients with chronic obstructive pulmonary disease admitted to our hospital were selected and randomly divided into 2 groups, with 48 cases in each group. The control group was treated with cefoperazone sulbactam, while the observation group was treated with cefoperazone sulbactam combined with ambroxol hydrochloride. Compare the therapeutic effects of the two groups. Results After treatment, the FVC and FEV1 in the observation group increased compared with those in the control group, while the CAT and mMRC scores decreased compared with those in the control group (P < 0.05). Conclusion The treatment effect of cefoperazone sulbactam combined with ambroxol hydrochloride for chronic obstructive pulmonary disease is better.
Key words： Chronic obstructive pulmonary disease; Cefoperazone sulbactam; Ambroxol hydrochloride
参考文献 References
[1] 冉莉. 痰热清联合头孢哌酮舒巴坦治疗慢性阻塞性肺疾病的临床疗效及其对炎性细胞因子水平的影响[J]. 临床合理用药杂志,2022,15(25):67-69.
[2] 杨雪. 头孢哌酮舒巴坦联合雾化吸入治疗慢性阻塞性肺疾病疗效观察及对患者肺功能、相关炎性介质表达的影响[J]. 智慧健康,2022,8(15):69-71.
[3] 梁政霞,张玲,林士军. 头孢哌酮舒巴坦并用盐酸氨溴索治疗慢阻肺的临床疗效分析[J]. 系统医学,2025,10(2): 66-69.
[4] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组,中国医师协会呼吸医师分会慢性阻塞性肺疾病工作委员会. 慢性阻塞性肺疾病诊治指南（2021年修订版）[J]. 中华结核和呼吸杂志,2021,44(3):170-205.
[5] 毛建军. 盐酸氨溴索联合头孢哌酮舒巴坦治疗慢性阻塞性肺疾病的临床效果及对肺功能的影响[J]. 临床合理用药,2024,17(31):67-70.
[6] 田维娜. 头孢哌酮舒巴坦联合盐酸氨溴索在中重度慢性阻塞性肺疾病急性加重期患者中的应用价值[J]. 中外医药研究,2025,4(16):58-60.
[7] 翟麦杏,王锦. 布地格福吸入联合头孢哌酮舒巴坦钠治疗慢性阻塞性肺疾病的效果及运动耐量观察[J]. 大医生,2025,10(5):139-141.
引用本文
潘海元, 蒯银伟, 头孢哌酮舒巴坦联合盐酸氨溴索治疗慢阻肺的研究[J]. 国际临床研究杂志, 2026; 10: (1) : 116-118.