Research on adverse reactions and prevention strategies of DTP vaccination
百白破疫苗预防接种反应及防治策略研究

摘要

目的 探讨百白破疫苗预防接种反应以及具体的防治策略。方法 此次研究对疾控中心2022年10月～2025年1月时间范围内的130例百白破疫苗预防接种儿童以分组的形式开展研究工作，通过随机数字表法划分为参照组（n=65）、研究组（n=65）共两个干预小组，并分别予以常规管理干预、风险管理接种干预，观察对比两组预防接种儿童的不良反应总发生率以及家属总满意度。结果 研究组预防接种儿童不良反应总发生率统计结果与参照组的统计结果相比呈现出的降低程度明显（P<0.05）；研究组预防接种儿童家属总满意度统计结果与参照组的结果相比表现出的提升程度明显（P<0.05）。结论 对于百白破疫苗预防接种儿童而言，存在一定概率表现出接种反应情况。在此种情形下，合理选择风险管理接种方式给予对应干预，可促进不良反应发生率的降低，获得较高的家属满意度。

Abstract

Objective To explore the adverse reactions to DTP (diphtheria, tetanus, pertussis) vaccination and specific prevention and treatment strategies.
Methods This study investigated 130 children who received DTP vaccination at the Center for Disease Control and Prevention from October 2022 to January 2025 through a grouped research design. According to a random number table method, the children were divided into a reference group (n=65) and a study group (n=65), forming two intervention groups. The reference group received routine management intervention, while the study group received risk management vaccination intervention. The total incidence of adverse reactions and overall family satisfaction of children in both groups were observed and compared.
Results The total incidence of adverse reactions in the study group was significantly lower compared to the reference group (P<0.05). The overall family satisfaction in the study group was significantly higher than that in the reference group (P<0.05).
Conclusion   Children receiving DTP vaccination may experience certain vaccination reactions. In this situation, reasonably selecting a risk management vaccination approach and providing corresponding interventions can help reduce the incidence of adverse reactions and achieve higher family satisfaction.