Application of sequential PICC with umbilical catheter in intravenous infusion therapy for critically ill preterm infants
脐静脉置管序贯PICC在危重症早产儿输液治疗中的应用

摘要

目的 深入探讨脐静脉置管（UVC）序贯经外周置入中心静脉导管（PICC）在危重症早产儿输液治疗中的应用效果，旨在为临床研究提供理论与实践依据，更好地为患儿生命健康保驾护航。方法 抽取2025年1月至2025年7月期间院内收治的危重症早产儿作为研究样本，共计56例，采用系统抽样法进行规范分组，分为参照组（n=28）和研究组（n=28）。参照组接受单纯PICC治疗，而研究组则接受脐静脉置管序贯PICC治疗。最终，对两组在PICC一次穿刺成功率、院内感染率、不良事件发生率及临床指标等方面进行综合评价和对比。结果 面对相同需求的患儿，采取不同形式的干预策略，所获效果也随之不同，研究组在各项指标数值的体现上均显优参照组，P值达小于0.05标准，值得探讨。结论 脐静脉置管序贯PICC技术在危重症早产儿输液治疗中的应用，不仅能显著提高穿刺成功率，减少多次穿刺引发的不良事件，从而减轻患儿的痛苦。同时，该技术还能有效提升治疗效率，降低治疗风险，对改善整体治疗效果具有积极影响，值得在临床中广泛推广。

Abstract

Objective To investigate the efficacy of umbilical vein catheterization (UVC) followed by peripherally inserted central venous catheterization (PICC) in intravenous therapy for critically ill preterm infants, providing theoretical and practical evidence to enhance clinical research and safeguard patients' health.
Methods A total of 56 critically ill preterm infants admitted between January and July 2025 were randomly assigned using systematic sampling into a control group (n=28) and an experimental group (n=28). The control group received standard PICC treatment, while the experimental group underwent UVC-sequential PICC therapy. Comprehensive evaluations compared both groups in terms of single-puncture success rate, hospital infection rates, adverse event incidence, and clinical outcomes.
Results When treating equivalent patient needs, different intervention strategies demonstrated distinct effects. The experimental group showed statistically significant advantages over the control group in all metrics (p<0.05), warranting further exploration.
Conclusion   The sequential UVC-PICC technique significantly improves puncture success rates, reduces complications from repeated procedures, and enhances treatment efficiency while lowering risks. This innovative approach demonstrates positive therapeutic outcomes and warrants broader clinical adoption.