The efficacy of levofloxacin combined with tinidazole in the acute attack stage of chronic pelvic inflammatory disease and its influence on the levels of inflammatory factors
左氧氟沙星联合替硝唑用于慢性盆腔炎急性发作期的疗效及对炎症因子水平的影响

摘要

目的 探讨左氧氟沙星联合替硝唑用于慢性盆腔炎急性发作期的疗效及对炎症因子水平的影响。方法 于2022年6月-2025年5月期间，选取100例慢性盆腔炎急性发作期患者为研究对象，数字随机表法将患者分为两组，对照组予以单药替硝唑进行治疗，观察组在此基础上联合左氧氟沙星治疗，对比治疗效果。结果 观察组较对照组治疗效果较为显著，对比有统计学意义（P＜0.05）；观察组较对照组炎症因子水平降低更加明显，对比有统计学意义（P＜0.05）。结论 在慢性盆腔炎急性发作期，予以左氧氟沙星联合替硝唑治疗，不仅治疗效果较为显著，还能帮助患者降低炎性因子水平。

Abstract

Objective To explore the efficacy of levofloxacin combined with tinidazole in the acute attack stage of chronic pelvic inflammatory disease and its influence on the levels of inflammatory factors.
Methods From June 2022 to May 2025, 100 patients with acute exacerbation of chronic pelvic inflammatory disease were selected as the research subjects. The patients were divided into two groups by digital random table method. The control group was treated with tinidazole monotherapy, while the observation group was treated with levofloxacin in combination on this basis. The therapeutic effects were compared.
Results The therapeutic effect of the observation group was more significant than that of the control group, and the comparison was statistically significant (P < 0.05). The levels of inflammatory factors in the observation group decreased more significantly than those in the control group, and the comparison was statistically significant (P < 0.05).
Conclusion   During the acute attack period of chronic pelvic inflammatory disease, the treatment with levofloxacin combined with tinidazole not only has a relatively significant therapeutic effect, but also helps patients reduce the levels of inflammatory factors.