摘要
总结1例Shwachman-Diamond综合症合并多重耐药菌感染行异基因造血干细胞移植的护理。因多重耐药菌感染、ADL分级为完全依赖，予发热护理与病情观察护理，稳定病情；予静脉置管护理有效预防静脉置管并发症，确保静脉用药治疗顺利进行；对于皮肤破溃与口腔溃疡，予皮肤护理及皮肤黏膜护理，患儿皮肤干裂部位均愈合，皮肤脱屑与口腔溃疡好转；对于营养不足，予饮食与营养支持护理，维持机体营养状态，提高抵抗力；对于负面情绪，予心理护理改善心理健康。患儿于+11d中性粒细胞植活，为1.6×10⁹g/L，顺利出层流室，移植后随访5个月病情稳定，ADL分级为部分自理。
关键词： 罕见病；多重耐药菌；感染；护理
Abstract
Summarize the nursing care of a case of Shwachman Diamond syndrome complicated with multidrug-resistant bacterial infection undergoing allogeneic hematopoietic stem cell transplantation. Due to multidrug-resistant bacteria and poor self-care ability, fever care and disease observation care should be provided to stabilize the condition; Effective prevention of complications caused by intravenous catheterization nursing ensures smooth progress of intravenous medication treatment; For skin ulceration and oral ulcers, skin care and skin mucosal care were provided. The dry and cracked areas of the child's skin healed, and the skin flaked and oral ulcers improved; For nutritional deficiencies, provide diet and nutritional support care to maintain the body's nutritional status and improve resistance; For negative emotions, provide psychological care to improve mental health. The patient's neutrophils were transplanted and the neutrophil count was 1.6 × 10 ⁹ g/L. The laminar flow room treatment was completed, and the patient's condition stabilized and their self-care ability recovered after a 3-month follow-up in the hospital.
Key words： Rare diseases; Multidrug resistant bacteria; Infected; Care
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