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Open Access Article

International Journal of Clinical Research. 2025; 9: (7) ; 76-80 ; DOI: 10.12208/j.ijcr.20250333.

Research and Clinical application progress of Xiakucao (Prunella vulgaris L.) on hepatocellular carcinoma
中药夏枯草抗肝癌的研究及应用进展

作者: 杜明舰, 陈太全, 李果, 秦超超 *

广元市中医医院肿瘤科 四川广元

*通讯作者: 秦超超,单位:广元市中医医院肿瘤科 四川广元;

发布时间: 2025-07-26 总浏览量: 37

摘要

夏枯草在抗肝细胞癌的治疗研究领域应用十分广泛。目前夏枯草抗肝癌的药理作用主要体现在抑制肝癌细胞增值,促进肝癌细胞凋亡等,在肝癌的中医临证应用中常与清利湿热、软坚散结等中药配伍使用。文章通过对夏枯草抗肝细胞癌的药理学机制和中医临证应用进行综述,总结了目前夏枯草在肝细胞癌治疗研究上的进展。

关键词: 夏枯草;中医病机;肝细胞癌;药理机制;抑制增殖;促进凋亡;信号通路;临证应用

Abstract

Traditional Chinese herb Xiakucao (Prunella vulgaris L.) is widely used in the field of anti-hepatocellular carcinoma treatment. At present, the pharmacological effects of Xiakucao (Prunella vulgaris L.) on hepatocellular carcinoma mainly include inhibiting the proliferation of tumor cells, promoting tumor cells apoptosis, etc. In the clinical application of traditional Chinese medicine for hepatocellular carcinoma, it is frequently used in combination with other traditional Chinese medicine with the effects of clearing dampness and heat, softening hardness and dispersing lumps. A review was conducted on the pharmacological mechanisms and clinical applications of Xiakucao (Prunella vulgaris L.) in the treatment of hepatocellular carcinoma, summarizing the current research and application of the herb in hepatocellular carcinoma.

Key words: Prunella vulgaris L; TCM pathogenesis; Hepatocellular carcinoma; Pharmacological mechanism; Inhibiting proliferation; Promoting apoptosis; Signal pathway; Clinical application

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引用本文

杜明舰, 陈太全, 李果, 秦超超, 中药夏枯草抗肝癌的研究及应用进展[J]. 国际临床研究杂志, 2025; 9: (7) : 76-80.