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当前位置：国际临床研究杂志 > 2025年 9卷 (6)期

Open Access Article

International Journal of Clinical Research. 2025; 9: (6) ; 57-60 ; DOI: 10.12208/j.ijcr.20250282.

The formation mechanism of venous thromboembolism (VTE) and the current status of its prevention
静脉血栓栓塞症（VTE）的形成机制及其预防研究现状

作者： 伊鑫¹, 李海峰^1,2 *

1 大理大学临床医学院云南大理

2 大理大学第二附属医院云南昆明

*通讯作者：李海峰,单位：大理大学第二附属医院云南昆明；

发布时间: 2025-06-26 总浏览量: 73

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摘要

静脉血栓栓塞症（VTE）包括深静脉血栓形成（DVT）和肺栓塞（PE），是一种高发病率、高致死率的血栓性疾病。其发病机制涉及血液成分异常、血管内皮损伤、炎症-免疫激活及遗传易感性等，多种因素交互作用导致凝血-纤溶失衡。目前预防策略基于风险评估，以机械和药物预防为核心。未来研究将聚焦于构建多维度风险预测模型与精准分层干预，以降低VTE的疾病负担。

关键词： 静脉血栓栓塞症；形成机制；风险评估；预防策略

Abstract

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a highly prevalent and lethal thrombotic disease. Its pathogenesis involves abnormalities in blood components, endothelial damage, inflammatory-immune activation, and genetic susceptibility, with multiple factors interacting to lead to coagulation-fibrinolytic imbalance. Current prevention strategies are based on risk assessment, with mechanical and pharmacological interventions at the core. Future research will focus on developing multidimensional risk prediction models and precise stratified interventions to reduce the burden of VTE.

Key words： Venous thromboembolism; Mechanism of formation; Risk assessment; Prevention strategies

参考文献 References

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引用本文

伊鑫, 李海峰, 静脉血栓栓塞症（VTE）的形成机制及其预防研究现状[J]. 国际临床研究杂志, 2025; 9: (6) : 57-60.

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