摘要
目的 探究儿童重症监护病房侵袭性真菌感染的特点。方法 选择我院儿童重症监护病房在2023年10月份至2024年10月份收治的30例侵袭性真菌感染的患儿进行研究，分析感染的临床特点，明确治疗以及转归。结果 30例患儿出现呼吸道感染的比例为90%；患儿发生感染之前存在严重的基础疾病，使用了多种抗生素，患儿存在侵入性操作史。有46.67%的患儿进行过机械通气治疗，患儿的临床症状并无特异性，影像学特异性不明显，进行真菌培养后，致病菌占比最高的为白色念珠菌；其次为曲霉菌；毛霉菌，为患者提供抗真菌药物治疗，有效的数量为25例，占比83.33%。结论 对于侵袭性真菌感染的患儿而言，在早期进行诊断，提供有效的抗真菌药物，可以改善患儿的预后。
关键词： 儿童重症监护病房；侵袭性真菌感染；临床特点
Abstract
Objective To explore the characteristics of invasive fungal infections in pediatric intensive care units. Methods 30 children with invasive fungal infection admitted from October 2023 to October 2024 were selected for study to analyze the clinical characteristics of the infection, and clarify the treatment and outcome. Results 90% of 30 children had respiratory infections; severe underlying disease before infection, multiple antibiotics, and a history of invasive procedures.46.67% of the children had mechanical ventilation, the clinical symptoms were not specific, imaging specificity is not obvious, after fungal culture, the highest proportion of Candida albicans; followed by illus, providing antifungal therapy, the effective number of 25 cases, accounting for 83.33%. Conclusion For children with invasive fungal infection, making an early diagnosis and providing effective antifungal drugs can improve their prognosis.
Key words： Pediatric intensive care unit; Invasive fungal infection; Clinical characteristics
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