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Open Access Article

International Journal of Clinical Research. 2025; 9: (4) ; 12-14 ; DOI: 10.12208/j.ijcr.20250174.

Research on the value of montelukast sodium as adjuvant treatment for pediatric bronchiolitis
孟鲁司特钠辅助治疗小儿毛细支气管炎的价值研究

作者: 黄慧 *

吉林市人民医院 吉林省吉林市

*通讯作者: 黄慧,单位:吉林市人民医院 吉林省吉林市;

发布时间: 2025-04-28 总浏览量: 23

摘要

目的 分析孟鲁司特钠辅助治疗小儿毛细支气管炎的价值。方法 挑选吉林市人民医院门诊两年期间收治的小儿毛细支气管炎患儿(样本纳入时间:2022年10月~2024年10月;样本纳入例数:86例)当作研究对象,以随机分组方法为分组原则,分为对照组(划分到该组的患儿进行布地奈德,n=43)与试验组(划分到该组的患儿进行孟鲁司特钠治疗,n=43)。对比两组的治疗效果及炎症指标。结果 在临床疗效上,试验组高于对照组(P<0.05)。在白细胞计数与C反应蛋白上,试验组低于对照组(P<0.05)。结论 孟鲁司特钠辅助治疗小儿毛细支气管炎的效果确切,有助于减轻肺部炎症反应,临床可进一步推广应用。

关键词: 小儿毛细支气管炎;孟鲁司特钠;治疗效果;炎症指标

Abstract

Objective To analyze the value of Montelukast Sodium as an adjuvant therapy for pediatric bronchiolitis.
Methods Children with bronchiolitis admitted to the outpatient department of Jilin People's Hospital during a two-year period (sample inclusion time: October 2022~October 2024; sample inclusion number: 86 cases) were selected as the research subjects. Random grouping was used as the grouping principle, and they were divided into a control group (children assigned to this group received budesonide, n=43) and an experimental group (children assigned to this group received montelukast sodium treatment, n=43). Compare the therapeutic effects and inflammatory indicators between the two groups.
Results In terms of clinical efficacy, the experimental group was higher than the control group (P<0.05). In terms of white blood cell count and C-reactive protein, the experimental group was lower than the control group (P<0.05).
Conclusion   Montelukast sodium has a definite effect as an adjuvant therapy for pediatric bronchiolitis, helping to reduce pulmonary inflammatory reactions, and can be further promoted and applied in clinical practice.

Key words: Pediatric bronchiolitis; Montelukast Sodium; Therapeutic effect; Inflammatory indicators

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引用本文

黄慧, 孟鲁司特钠辅助治疗小儿毛细支气管炎的价值研究[J]. 国际临床研究杂志, 2025; 9: (4) : 12-14.