Effect of recombinant human interferon α-2b gel in the treatment of chronic cervicitis combined with high-risk HPV infection
重组人干扰素α-2b凝胶治疗慢性宫颈炎合并高危型HPV感染的效果

摘要

目的 观察慢性宫颈炎合并HPV感染（高危型）患者接受重组人干扰素α-2b凝胶治疗的疗效。方法 选择于2023年11月至2024年11月在我院就医的慢性宫颈炎合并HPV感染（高危型）患者84例，以入院先后顺序分组，对照组42例，开展复方沙棘籽油栓治疗，治疗组42例，开展重组人干扰素α-2b凝胶治疗，对临床疗效进行分析和对比。结果 临床疗效对比，治疗组（95.24%）优于对照组（76.19%）（P<0.05）；炎性因子水平对比，治疗组治疗后优于对照组（P<0.05）。结论 慢性宫颈炎合并HPV感染（高危型）患者接受重组人干扰素α-2b凝胶治疗效果良好，值得推广。

Abstract

Objective To observe the efficacy of recombinant human interferon α-2b gel in the treatment of patients with chronic cervicitis combined with HPV infection (high-risk type).
Methods A total of 84 patients with chronic cervicitis combined with HPV infection (high-risk type) who were treated in our hospital from November 2023 to November 2024 were selected and divided into groups according to the order of admission. The control group of 42 cases was treated with compound seabuckthorn seed oil suppository, and the treatment group of 42 cases was treated with recombinant human interferon α-2b gel. The clinical efficacy was analyzed and compared.
Results The clinical efficacy of the treatment group (95.24%) was better than that of the control group (76.19%) (P<0.05); the level of inflammatory factors was compared, and the treatment group was better than the control group after treatment (P<0.05).
Conclusion   The treatment effect of recombinant human interferon α-2b gel on patients with chronic cervicitis combined with HPV infection (high-risk type) is good and worth promoting.