Clinical study on the combination of domperidone and compound digestive enzymes in the treatment of functional dyspepsia
多潘立酮联合复方消化酶治疗功能性消化不良的临床研究

摘要

目的 分析在功能性消化不良患者的治疗方案中应用多潘立酮联合复方消化酶治疗的医学价值。方法 将2022年1月-2023年12月内于本院就诊的功能性消化不良患者100例随机分50例对照组实施多潘立酮治疗，50例观察组联合复方消化酶治疗。对比治疗后的中医症状积分、治疗前后的胃部激素水平。结果 治疗前，两组对比无统计学意义（P﹥0.05）。而治疗后，观察组胃部激素优于对照组，且治疗后的临床症状评分低于对照组，指标对比有统计学意义（P﹤0.05）。结论 在功能性消化不良患者的治疗方案中应用多潘立酮联合复方消化酶治疗可缓解胃部不适纳差等症状，促进胃部功能改善。

Abstract

Objective To analyze the medical value of using domperidone combined with compound digestive enzymes in the treatment of patients with functional dyspepsia.
Methods 100 patients with functional dyspepsia who visited our hospital from January 2022 to December 2023 were randomly divided into a control group of 50 patients who received treatment with domperidone, and an observation group of 50 patients who received treatment with compound digestive enzymes. Compare the Integral of Symptom in traditional Chinese medicine after treatment and the levels of gastric hormones before and after treatment.
Results Before treatment, there was no statistically significant difference between the two groups (P>0.05). After treatment, the observation group had better gastric hormones than the control group, and the clinical symptom score after treatment was lower than that of the control group, with statistical significance in the comparison of indicators (P<0.05).
Conclusion   The application of domperidone combined with compound digestive enzymes in the treatment plan of patients with functional dyspepsia can alleviate symptoms such as gastric discomfort and poor appetite, and promote the improvement of gastric function.