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Open Access Article

International Journal of Clinical Research. 2025; 9: (2) ; 187-189 ; DOI: 10.12208/j.ijcr.20250112.

Clinical efficacy analysis of dexmedetomidine assisted general anesthesia treatment
右美托咪啶辅助全身麻醉治疗的临床效果分析

作者: 赖雨婷 *

郁南县人民医院 广东云浮

*通讯作者: 赖雨婷,单位:郁南县人民医院 广东云浮;

发布时间: 2025-02-14 总浏览量: 71

摘要

目的 分析全身麻醉病人采取右美托咪啶辅助治疗所体现的临床价值。方法 纳入本院2023年4月~2024年4月手术治疗全身麻醉患者,全部130例随机划分2组分别65例。2组采取相同的麻醉诱导,对照组采取静脉注射生理盐水辅助全身麻醉,观察组采取静脉注射右美托咪啶辅助全身麻醉。根据麻醉效果、应激反应进行评价。结果 对比2组Ramsay镇静评分,观察组麻醉后5分钟、15分钟评分较对照组均增加(P<0.05)。对比2组皮质醇、去甲肾上腺素水平,观察组麻醉后较对照组均下降(P<0.05)。结论 全身麻醉病人采取右美托咪啶辅助治疗可以提升麻醉效果,有助于减轻应激反应。

关键词: 全身麻醉;右美托咪啶;辅助治疗

Abstract

Objective To analyze the clinical value of using dexmedetomidine as adjuvant therapy in patients undergoing general anesthesia.
Methods 130 patients who underwent general anesthesia surgery in our hospital from April 2023 to April 2024 were randomly divided into two groups, with 65 patients in each group. Two groups received the same anesthesia induction, the control group received intravenous injection of physiological saline as an auxiliary general anesthesia, and the observation group received intravenous injection of dexmedetomidine as an auxiliary general anesthesia. Evaluate based on anesthesia effect and stress response.
Results the Ramsay sedation scores of the two groups, the observation group showed an increase in scores at 5 and 15 minutes after anesthesia compared to the control group (P<0.05). Comparing the levels of cortisol and norepinephrine in two groups, the observation group showed a decrease after anesthesia compared to the control group (P<0.05).
Conclusion   Adjuvant treatment with dexmedetomidine can improve anesthesia efficacy and help alleviate stress reactions in patients undergoing general anesthesia.

Key words: General anesthesia; Dexmedetomidine; Adjuvant therapy

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引用本文

赖雨婷, 右美托咪啶辅助全身麻醉治疗的临床效果分析[J]. 国际临床研究杂志, 2025; 9: (2) : 187-189.