Clinical observation of arthroscopic debridement combined with PRP in the treatment of knee osteoarthritis
关节镜下清理术联合PRP治疗膝关节骨性关节炎的临床观察

摘要

目的 探析关节镜清理术与富血小板血浆（Platelet-Rich Plasma, PRP）联合疗法在膝关节骨性关节炎治疗中的临床效用。方法 以2024年3月至8月间，我院纳入的50例膝关节骨性关节炎患者作为研究样本，并依据治疗方案差异，将其分为参考组与实验组，每组均含25例，参考组实施单一关节镜下清理术，而实验组则采用关节镜下清理术结合PRP治疗。对比两组疗效。结果 相较于参考组，实验组术后在Lysholm评分上表现更优，VAS评分则明显更低（P<0.05）；治疗有效率显著更高（P<0.05）；且并发症发生率明显更低（P<0.05）。结论 采用关节镜清理术结合PRP疗法治疗膝关节骨性关节炎疗效显著，具有在临床实践中进一步推广的价值。

Abstract

Objective Investigating the therapeutic effectiveness of combining arthroscopic cleaning with platelet-rich plasma for the management of knee osteoarthritis.
Methods 50 patients diagnosed with knee osteoarthritis and admitted to our facility between March and August 2024 were chosen as study participants. Based on their treatment approaches, they were allocated into a control group and an experimental group, comprising 25 patients each. The control group underwent arthroscopic debridement, whereas the experimental group underwent arthroscopic debridement augmented with PRP therapy. A comparison was made between the two groups in terms of knee function, pain intensity, therapeutic outcomes, and complication rates.
Results Postoperatively, the experimental group exhibited notably higher Lysholm scores and markedly lower VAS scores compared to the reference group (P<0.05). The experimental group demonstrated a significantly superior treatment efficacy (P<0.05), along with a considerably lower incidence of complications (P<0.05).
Conclusion   The combination of arthroscopic debridement and PRP therapy for knee osteoarthritis shows remarkable improvement in patients' knee function, pain relief, clinical effectiveness, and a decrease in complication rates. This approach merits further clinical promotion and adoption.