摘要
目的 探讨内镜下组织胶注射治疗高危消化性溃疡出血的临床分析。方法 选择我院于2023年1月-2024年1月内收治的100例高危消化性溃疡出血患者为研究对象，将其按随机数字表分组方法分为对照组（50例）和观察组（50例），对照组采用内镜下注射1∶10000肾上腺素治疗，观察组采用内镜下注射组织胶治疗。对两组患者的临床治疗效果、再出血发生率、治疗指标（止血时间、腹痛消失时间、肠胃功能恢复时间、住院时间）以及并发症发生率进行对比与评估。结果 观察组患者的临床治疗效果优于对照组（P＜0.05）。观察组患者的再出血发生率与并发症发生率均低于对照组（P＜0.05）。观察组患者的各项治疗指标均优于对照组（P＜0.05）。结论 在对高危消化性溃疡出血患者实施内镜下组织胶注射治疗可取得明显效果，显著缩短止血和治疗时间，降低并发症发生率和再出血发生率。值得在临床中推广应用。
关键词： 内镜下组织胶注射治疗；高危消化性溃疡出血；止血时间；并发症
Abstract
Objective Exploring the clinical analysis of endoscopic injection of tissue glue for the treatment of high-risk peptic ulcer bleeding. Methods Selecting 100 high-risk patients with peptic ulcer bleeding admitted to our hospital from January 2023 to January 2024 as the research subjects, they were randomly divided into a control group (50 cases) and an observation group (50 cases) according to a random number table method. The control group was treated with endoscopic injection of 1:10000 adrenaline, while the observation group was treated with endoscopic injection of tissue glue. Compare and evaluate the clinical treatment efficacy, incidence of rebleeding, treatment indicators (hemostasis time, disappearance time of abdominal pain, recovery time of gastrointestinal function, length of hospital stay), and incidence of complications between two groups of patients. Results The clinical treatment effect of the observation group was better than that of the control group (P<0.05). The incidence of rebleeding and complications in the observation group was lower than that in the control group (P<0.05). The treatment indicators of the observation group were superior to those of the control group (P<0.05). Conclusion Endoscopic tissue gel injection therapy can achieve significant results in high-risk patients with peptic ulcer bleeding, significantly shorten hemostasis and treatment time, and reduce the incidence of complications and rebleeding. It is worth promoting and applying in clinical practice.
Key words： Endoscopic tissue glue injection therapy; High risk peptic ulcer bleeding; Hemostasis time; Complication
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