Exploration of the effects of progesterone and progesterone on threatened miscarriage and their impact on hormone levels
黄体酮与地屈孕酮治疗先兆流产的效果及对激素水平的影响探讨

摘要

目的 观察对先兆流产患者使用黄体酮与地屈孕酮治疗的效果以及针对患者激素水平的影响。方法在2023年5月至2024年6月本院先兆流产患者中选择70例，按照随机抽样划分对照组（35例，服用黄体酮治疗），观察组（35例，服用地屈孕酮治疗）。针对两组疼痛程度、阴道出血量以及雌二醇、孕酮、人绒毛膜促性腺激素对比。结果 观察组治疗后疼痛程度、阴道出血量均低于对照组，P<0.05。雌二醇、孕酮、人绒毛膜促性腺激素水平检测，治疗后观察组均高于对照组，P<0.05。整体治疗效果统计，观察组有效率达94.29%（33/35），包括显效患者23例，有效患者10例，对照组有效率达71.43%（25/35），包括显效患者15例，有效患者10例，P<0.05。结论 在对先兆流产患者治疗时选择地屈孕酮进行治疗，可以更加有效针对患者激素水平进行改善，有效缓解患者疼痛症状，并降低患者阴道出血量，能够起到促进患者进行恢复的目的。

Abstract

Objective To observe the effect of using progesterone and dexamethasone in the treatment of threatened miscarriage patients and their impact on hormone levels.
Methods From May 2023 to June 2024, 70 patients with threatened miscarriage in our hospital were selected and randomly divided into a control group (35 cases, treated with progesterone) and an observation group (35 cases, treated with dexamethasone). Comparison of pain levels, vaginal bleeding volume, estradiol, progesterone, and human chorionic gonadotropin between two groups.
Results The pain level and vaginal bleeding volume in the observation group were lower than those in the control group after treatment, with P<0.05. The levels of estradiol, progesterone, and human chorionic gonadotropin were detected, and the observation group was higher than the control group after treatment, with P<0.05. According to the overall treatment effect statistics, the effective rate of the observation group was 94.29% (33/35), including 23 significantly effective patients and 10 effective patients. The effective rate of the control group was 71.43% (25/35), including 15 significantly effective patients and 10 effective patients, with P<0.05.
Conclusion   Choosing progesterone for the treatment of threatened miscarriage patients can effectively improve their hormone levels, alleviate their pain symptoms, and reduce vaginal bleeding, which can promote their recovery.