Open Access Article
International Journal of Clinical Research. 2025; 9: (2) ; 13-16 ; DOI: 10.12208/j.ijcr.20250062.
Evaluation of the effect of recombinant collagen antibacterial gel for women on gynecological diseases and the influence of cervical human papillomavirus infection
重组胶原蛋白妇用阻菌凝胶对妇科疾病的效果评价及宫颈人乳头状瘤病毒感染患者的影响
作者:
赵卫红1 *,
刘玉新2
1首都医科大学附属北京天坛医院 北京
2吉林省司诺健康实业集团有限公司 吉林长春
*通讯作者:
赵卫红,单位:首都医科大学附属北京天坛医院 北京;
发布时间: 2025-02-11 总浏览量: 298
PDF 全文下载
引用本文
摘要
目的 分析重组胶原蛋白妇用阻菌凝胶对妇科疾病的效果评价及宫颈人乳头状瘤病毒(HPV)感染患者的影响。方法 选择我院2023年1月-2024年1月期间收治的妇科疾病及宫颈人乳头状瘤病毒感染患者150例,将其按随机分组方法分为对照组(75例)和观察组(75例,采取重组胶原蛋白妇用阻菌凝胶治疗),对比两组在宫颈炎、阴道炎、支原体衣原体感染、阴道萎缩紧致、阴道干涩及HPV感染等方面的治疗效果。结果 观察组患者在宫颈炎、阴道炎、支原体衣原体感染、阴道萎缩紧致及阴道干涩同房疼痛等方面的治疗效果均优于对照组(P<0.05)。观察组患者HPV载量低于对照组(P<0.05)。结论 在对妇科疾病及宫颈人乳头状瘤病毒感染患者实施重组胶原蛋白妇用阻菌凝胶治疗取得明显的效果,有较高应用价值,值得临床推广与应用。
关键词: 重组胶原蛋白妇用阻菌凝胶;妇科疾病;宫颈人乳头状瘤病毒;效果评价
Abstract
Objective To analyze the effect of recombinant collagen antibacterial gel on gynecological diseases and the impact of cervical human papillomavirus infection. Methods 150 patients with gynecological diseases and cervical human papillomavirus infection admitted to our hospital from January 2023 to January 2024 were randomly divided into the control group (75 cases) and the observation group (75 cases, treated with recombinant collagen for women with antibacterial gel). The therapeutic effects of the two groups on cervicitis, vaginitis, chlamydia mycoplasma infection, vaginal atrophy and tightness, vaginal dryness and HPV infection were compared. Results The treatment effects of the observation group patients in terms of cervicitis, vaginitis, mycoplasma and chlamydia infection, vaginal atrophy and tightness, and vaginal dryness and pain during intercourse were better than those of the control group (P<0.05). The HPV load in the observation group was lower than that in the control group (P<0.05). Conclusion In the treatment of gynecological diseases and cervical human papillomavirus infection patients, the recombinant collagen gynecological bacteria blocking gel has achieved obvious results, has high application value, and is worthy of clinical promotion and application.
Key words: Recombinant collagen antibacterial gel for women; Gynecological diseases; Cervical human papillomavirus; Impact assessment
参考文献 References
[1] 陈敏.重组人干扰素α2b阴道泡腾片联合保妇康栓治疗宫颈高危型人乳头瘤病毒感染患者的临床效果及对炎症因子的影响[J].妇儿健康导刊,2023,2(06):117-119.
[2] 刘敏君,刘清花,罗强,等.重组人干扰素α-2b凝胶联合乳酸菌阴道胶囊对高危型人乳头瘤病毒感染患者阴道微生态的影响[J].当代医学, 2024, 30(5):67-70.
[3] 陈梦捷,张三元,徐迎亚,等.重组Ⅲ型人源化胶原蛋白冻干纤维治疗阴道松弛症随机对照临床试验研究[J]. 中国实用妇科与产科杂志,2024,40(6):665-668.
[4] 胡文波,董亚宁.重组人干扰素α-2b栓、多西环素联合完带汤治疗宫颈支原体感染疗效观察[J].现代中西医结合杂志(23期):2602-2604[2024-12-24].
[5] 柯水英.重组人干扰素α-2b栓联合阿奇霉素治疗宫颈衣原体及支原性感染的临床观察[J].当代医学, 2018, 24(7):2.
[6] 游爽. Ⅲ型胶原蛋白对大鼠阴道萎缩的作用及机制研究[D]. 重庆:重庆医科大学,2020.
[7] 董晓静,郭雪桃,游爽,等.重组Ⅲ型人源化胶原蛋白阴道凝胶治疗阴道干涩临床研究[J]. 中国实用妇科与产科杂志,2022,38(6):657-660.
[8] 李娟,田甜,冯永波,等.重组人干扰素α-2b凝胶联合乳酸菌阴道胶囊治疗子宫颈高危型人乳头瘤病毒持续感染的效果[J].中外医学研究,2022,20(11):60-63.
引用本文
赵卫红, 刘玉新, 重组胶原蛋白妇用阻菌凝胶对妇科疾病的效果评价及宫颈人乳头状瘤病毒感染患者的影响[J]. 国际临床研究杂志, 2025; 9: (2) : 13-16.