Open Access Article
International Journal of Clinical Research. 2025; 9: (2) ; 4-6 ; DOI: 10.12208/j.ijcr.20250059.
Effect of Xianling Gubao Capsule on Type 2 diabetes mellitus complicated with Osteoporosis
仙灵骨葆胶囊治疗2型糖尿病合并骨质疏松症的效果
作者:
杨浩杰1,
牛灵芝1,
张玉磊1,
卢媛媛1,
王辉2 *
1西安交通大学医院 陕西西安
2西安交通大学第一附属医院 陕西西安
*通讯作者:
王辉,单位:西安交通大学第一附属医院 陕西西安;
发布时间: 2025-02-11 总浏览量: 141
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摘要
目的 明确仙灵骨葆胶囊对2型糖尿病合并骨质疏松症(Osteoporosis,OP)患者的效果,旨在推动2型糖尿病合并OP治疗研究发展。方法 研究纳入2023年11月-2024年11月中综合临床各项检查结果满足2型糖尿病合并OP诊断标准的95例患者,对各个患者进行随机编号后采取随机抽取法安排为两组,对照组与观察组分别49、46例,对照组行常规治疗干预,观察组行仙灵骨葆胶囊干预,对不同干预效果进行比较分析。结果 与对照组相比,观察组骨密度(Bone Mineral Density,BMD)数值更高,观察组临床症状持续时间更短,有显著性差异(P<0.05)。结论 于2型糖尿病合并OP患者中施以仙灵骨葆胶囊措施,可促进BMD相关指标恢复,缩短临床症状持续时长。
关键词: 2型糖尿病;骨质疏松症;仙灵骨葆胶囊
Abstract
Objective To clarify the effect of Xianling Gubao Capsule on patients with type 2 diabetes mellitus complicated with osteoporosis, and to promote the research and development of the treatment of type 2 diabetes mellitus complicated with osteoporosis. Methods A total of 95 patients who met the diagnostic criteria for type 2 diabetes mellitus complicated with osteoporosis were enrolled in this study from November 2023 to mid-November 2024, and the patients were randomly numbered and arranged into two groups, 49 cases in the control group and 46 cases in the observation group, respectively. The control group administered conventional therapeutic intervention and the observation group administered the fairy bone capsule intervention. The effects of the different interventions were compared and analyzed. Results Compared with the control group, the observation group had higher bone mineral density value and shorter duration of clinical symptoms, there was significant difference (P<0.05). Conclusion The administration of Xianling Gubao Capsule can promote the recovery of bone mineral density related indexes and shorten the duration of clinical symptoms in patients with type 2 diabetes mellitus complicated with osteoporosis.
Key words: Type 2 diabetes mellitus; Osteoporosis; Xianling Gubao Capsule
参考文献 References
[1] 高明. 观察围绝经期2型糖尿病骨质疏松症治疗中胰岛素与阿仑膦酸钠的联合应用效果[J]. 中国现代药物应用,2021,15(2):201-203.
[2] 张艺露,白雪剑,高九青. 西格列汀联合唑来膦酸与二甲双胍治疗2型糖尿病合并骨质疏松症对患者骨代谢及胰岛素抵抗的影响[J]. 中国药物经济学,2024,19(2):57-60,65.
[3] 杨明明,张友生,姚媛莉,等. 利拉鲁肽联合阿仑膦酸钠治疗2型糖尿病合并骨质疏松症的效果[J]. 西北药学杂志,2024,39(6):212-216.
[4] 宋延龙. 温针灸联合仙灵骨葆胶囊治疗类风湿关节炎合并2型糖尿病患者的疗效评价[J]. 实用糖尿病杂志,2020,16(6):61-62.
[5] 曾莉,阳玲,方涛,等. 2型糖尿病患者骨代谢指标的变化及应用仙灵骨葆胶囊治疗的疗效观察[J]. 四川生理科学杂志,2024,46(3):514-516.
[6] 李慧,刘彦合,黄明龙,等. 仙灵骨葆胶囊联合阿仑膦酸钠和二甲双胍治疗老年2型糖尿病伴发骨质疏松症疗效分析[J]. 国际老年医学杂志,2021,42(3):155-157.
[7] 艾力亚斯·阿不拉. 仙灵骨葆胶囊联合唑来膦酸注射液治疗糖尿病性骨质疏松患者69例[J]. 西部中医药,2020, 33(10):120-124.
[8] 张瑞娟,焦杰. 仙灵骨葆胶囊联合阿仑膦酸钠治疗2型糖尿病合并骨质疏松症的效果及安全性观察[J]. 大医生,2024,9(13):90-92.
引用本文
杨浩杰, 牛灵芝, 张玉磊, 卢媛媛, 王辉, 仙灵骨葆胶囊治疗2型糖尿病合并骨质疏松症的效果[J]. 国际临床研究杂志, 2025; 9: (2) : 4-6.