摘要
目的 分析高血压合并冠心病治疗采用血脂康+阿托伐他汀的效果。方法 选取我院高血压合并冠心病患者进行研究,选取病例数50例,选取时间段2023年10月-2024年6月,数字排序分组,双数25例为对照组采用阿托伐他汀,单数25例为观察组加用血脂康,对两组心功能指标、血压指标及不良反应进行比较。结果 与对照组相较,观察组心功能指标及血压指标更优,差异均有统计学意义(P<0.05),不良反应无统计学意义(P>0.05)。结论 高血压合并冠心病治疗采用血脂康+阿托伐他汀的效果更优,更利于改善心功能及血压指标,且不增加不良反应,应用安全性高,更利于促进机体恢复。
关键词: 血脂康;阿托伐他汀;高血压;冠心病;治疗
Abstract
Objective To analyze the effect of using Xuezhikang+atorvastatin in the treatment of hypertension combined with coronary heart disease. Methods A study was conducted on patients with hypertension and coronary heart disease in our hospital. A total of 50 cases were selected and the time period was from October 2023-June 2024. The patients were divided into two groups based on numerical sorting: the control group (25 cases with even numbers) was treated with atorvastatin, and the observation group (25 cases with odd numbers) was treated with Xuezhikang. The cardiac function indicators, blood pressure indicators, and adverse reactions of the two groups were compared. Results Compared with the control group, the observation group had better cardiac function and blood pressure indicators, and the differences were statistically significant (P<0.05). There was no statistically significant adverse reaction (P>0.05). Conclusion The treatment of hypertension combined with coronary heart disease using Xuezhikang+atorvastatin has a better effect, is more conducive to improving heart function and blood pressure indicators, does not increase adverse reactions, has high safety, and is more conducive to promoting body recovery.
Key words: Xuezhikang; Atorvastatin; hypertension; Coronary heart disease; Treatment
参考文献 References
[1] 吴文学,龚黎斌,施长红. 阿托伐他汀钙不同剂量治疗老年冠心病患者临床效果及安全性比较 [J]. 天津药学, 2024, 36 (04): 65-68.
[2] 梁岩,周彬,程艳玲. 血脂康联合阿托伐他汀对老年糖尿病动脉粥样硬化合并高血压患者血脂水平影响 [J]. 临床军医杂志, 2024, 52 (03): 291-293.
[3] 王佳星,吴洁琼,李红月. 血脂康联合阿利西尤单抗对他汀类药物不耐受动脉粥样硬化性心血管疾病患者LDL-C达标率和其他血脂指标影响 [J]. 转化医学杂志, 2024, 13 (01): 11-15.
[4] 《中国心血管健康与疾病报告》2023(冠心病部分内容) [J]. 心肺血管病杂志, 2024, 43 (10): 1015-1024.
[5] 曾学寨,刘德平. 《2024年ESC血压升高和高血压管理指南》解读 [J]. 中国心血管杂志, 2024, 29 (05): 400-403.
[6] 凌永珍,吴露仙,廖海伟. 血脂康胶囊对老年高血压左室肥厚患者动脉硬化程度和左室重构的影响 [J]. 临床合理用药, 2023, 16 (25): 14-17+21. D
[7] 刘羿杉. 血脂康联合阿托伐他汀治疗对冠状动脉粥样硬化性心脏病合并高脂血症降脂效果及其心血管事件的影响 [J]. 中国药物经济学, 2022, 17 (09): 89-92.
[8] 李绪贵. 血脂康联合阿托伐他汀对老年高血压合并冠心病患者血压、血脂及炎性因子的影响 [J]. 河北医药, 2022, 44 (17): 2667-2669.
[9] 岳龙华. 血脂康胶囊与阿托伐他汀钙片治疗老年腔隙性脑梗死伴高脂血症、高血压前期患者的临床效果比较 [J]. 临床医学研究与实践, 2020, 5 (27): 16-17+22.
[10] 罗世芳. 阿托伐他汀钙+血脂康治疗冠心病的临床效果与安全性研究 [J]. 实用中西医结合临床, 2022, 22 (16): 10-13.