Open Access Article
International Journal of Clinical Research. 2025; 9: (1) ; 1-4 ; DOI: 10.12208/j.ijcr.20250001.
One case of reversible posterior encephalopathy syndrome and literature review
可逆性后部脑病综合征1例并文献综述
作者:
张姣,
田季雨 *,
张军,
常晓琳,
石娟娜
中国人民解放军第63750部队医院 陕西西安
*通讯作者:
田季雨,单位:中国人民解放军第0部队医院 陕西西安;
发布时间: 2025-01-10 总浏览量: 183
PDF 全文下载
引用本文
摘要
可逆性后部脑病综合征是一组临床影像学综合征,病因多种多样,大多合并较严重的基础疾病。PRES中最常见的神经影像学异常累及大脑后半球的皮质下白质,尤其是双侧顶叶和枕叶区域。PRES与双侧大脑后动脉梗死的区别是距状裂和枕叶中线旁结构通常保留。多数PRES患者的枕叶和顶叶均出现双侧水肿病变。本文报道一例癫痫发作后头痛伴视物模糊的患者,通过头颅MRI检查确诊PRES,经脱水、改善循环、对症等治疗后,患者预后较好,临床症状和影像学改变完全消失,从而增强临床医师对该病的认识。本文将该例患者诊疗经过进行总结,以期为相关病历作参考。
关键词: 可逆性后部脑病综合征;影像学;大脑后半球;头颅MRI
Abstract
Reversible posterior encephalopathy syndrome is a clinical imaging syndrome with various etiologies, mostly accompanied by more severe underlying diseases. The most common neuroimaging abnormalities in PRES involve subcortical white matter in the posterior hemisphere of the brain, especially in the bilateral parietal and occipital lobes. The difference between PRES and bilateral posterior cerebral artery infarction is that the structures adjacent to the midline of the occipital lobe and the spinous fissure are usually preserved. Most PRES patients have bilateral edema lesions in the occipital and parietal lobes. This article reports a patient with post-stroke pain and blurred vision who was diagnosed with Pres through cranial MRI examination. After dehydration, improvement of circulation, symptomatic treatment, etc., the patient's prognosis was good, and clinical symptoms and imaging changes completely disappeared, thereby enhancing clinical physicians' understanding of the disease. This article summarizes the diagnosis and treatment process of the patient in order to provide reference for relevant medical records.
Key words: Reversible posterior encephalopathy syndrome; Imaging; Posterior hemisphere of the brain; Head MRI
参考文献 References
[1] Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996;334(8):494–500.
[2] Ismail FS, van de Nes J, Kleffner I.A broad spectrum of posterior reversible encephalopathy syndrome - a case series with clinical and paraclinical characterisation, and histopathological findings.BMC Neurol. 2021 Oct 6;21(1):386.
[3] 唐乐丽,黄怡蝶,张迅捷,等.1例肾病综合征患儿他克莫司相关可逆性后部脑病综合征的药学监护[J].医药导报,2024,43(2):292-298.
[4] 李佐峰,熊昊,陈智,等.儿童异基因造血干细胞移植后可逆性后部脑病综合征的临床分析[J].中国实验血液学杂志,2024,32(5):1560-1565.
[5] 相玲丽,张凯,邵勇.基于Web of Science数据库可逆性后部脑病综合征研究的可视化分析[J].国际医药卫生导报,2024,30(5):713-720.
[6] 刘安利,薛茜,苗瑞瑞.2019冠状病毒疾病大流行背景下可逆性后部脑病综合征的特点分析[J].中国临床神经外科杂志,2024,29(4):243-247.
[7] 赵鑫,薛伟,祝新莉,等.阵发性睡眠性血红蛋白尿症伴可逆性后部脑病综合征1例报道[J].中国卒中杂志,2024, 19(6):699-705.
[8] 欧盟采取措施降低伪麻黄碱可逆性后部脑病综合征和可逆性脑血管收缩综合征风险[J].中国药物评价,2024, 41(1):30-30.
引用本文
张姣, 田季雨, 张军, 常晓琳, 石娟娜, 可逆性后部脑病综合征1例并文献综述[J]. 国际临床研究杂志, 2025; 9: (1) : 1-4.