Observation of the effect of laparoscopic ovariostomy combined with letrozole in the treatment of refractory polycystic ovary syndrome
腹腔镜下卵巢打孔术联合来曲唑治疗难治性多囊卵巢综合征的效果观察

摘要

目的 为提高难治性多囊卵巢综合征的治疗效果，改善女性生殖健康，下文将围绕腹腔镜下卵巢打孔术联合来曲唑治疗的干预效果开展分析观察，为推广提供数据支持。方法 实验开展确定时间为：2023年1月至2023年12月期间，实验样本来源均选自于该期间收治难治性多囊卵巢综合征患者，涉及样本量共计80例，为患者详细讲解实验目的后由专职人员引导患者完成入组，即腹腔镜下卵巢打孔术、来曲唑治疗联合治疗（观察组n=40）、单一腹腔镜下卵巢打孔术治疗（对照组n=40），整理记录不同治疗后两组患者相关数据指标，并借助统计学系统完成分析对比，观察结果差异表现。结果 治疗3个月后两组患者PRL、E2 水平对比P＞0.05；观察组患者FSH 水平、LH、T、LH、FSH 及 AMH 、激素水平、妊娠率、流产率均优于对照组P＜0.05。结论 难治性多囊卵巢综合征患者实施腹腔镜下卵巢打孔术、来曲唑治疗联合治疗对患者功能的影响具有积极意义，对妊娠率的提升有明显作用，应用价值明显，值得推广。

Abstract

Objective In order to improve the treatment effect of refractory polycystic ovary syndrome and improve female reproductive health, the following will analyze and observe the intervention effect of laparoscopic ovariectomy combined with letrozole treatment, and provide data support for promotion.
Methods The experiment was carried out at the following time: From January 2023 to December 2023, the experimental samples were all selected from patients with refractory polycystic ovary syndrome treated during this period, involving a total sample size of 80 cases. After explaining the experimental purpose in detail, full-time staff guided the patients to complete the enrollment. That is, laparoscopic ovariectomy, letrozole combined treatment (observation group n=40), and single laparoscopic ovariectomy (control group n=40). Relevant data indexes of patients in the two groups after different treatments were sorted out and recorded, and analyzed and compared with the statistical system to observe the difference in results.
Results After 3 months of treatment, the levels of PRL and E2 were compared between the two groups (P > 0.05). FSH level, LH, T, LH, FSH and AMH, hormone level, pregnancy rate and abortion rate in observation group were superior to those in control group (P < 0.05).
Conclusion   The combined treatment of laparoscopic ovariostomy and letrozole in patients with refractory polycystic ovary syndrome has a positive effect on the function of the patients, and has a significant effect on the improvement of pregnancy rate.