Clinical effect of amiodarone on tachyarrhythmia of emergency coronary heart disease
胺碘酮治疗急诊冠心病快速心律失常的临床疗效

摘要

目的 研究分析胺碘酮治疗急诊冠心病快速心律失常的临床疗效。方法 选取2023年10月至2024年10月期间于我院急诊科进行治疗的冠心病快速心率失常患者105例为研究对象，随机分为试验组（55例）与参照组（50例），分别予胺碘酮、普罗帕酮进行治疗，比较治疗有效率、心功能指标水平及生活质量。结果 （1）经比较，试验组临床治疗有效率明显更高，数据有统计学意义（P＜0.05）；（2）经治疗，试验组左心室舒张末期内径（LVEDD）与左心室收缩期末期内径（LVESD）均明显低于参照组，且试验组左心室射血分数（LVEF）与心输出量（CO）明显高于参照组，数据有统计学意义（P＜0.05）；（3）经治疗，试验组生活质量评分明显高于参照组，数据有统计学意义（P＜0.05）。结论 应用胺碘酮治疗急诊冠心病快速心率失常，临床效果显著，既能明显改善患者的心功能，还能明显提升患者生活质量，值得推广。

Abstract

Objective To study and analyze the clinical efficacy of amiodarone in the treatment of tachyarrhythmias in emergency coronary heart disease.
Methods A total of 105 patients with tachyarrhythmias in coronary heart disease who were treated in the emergency department of our hospital from October 2023 to October 2024 were selected as the research subjects and randomly divided into the experimental group (55 cases) and the reference group (50 cases). They were treated with amiodarone and propafenone respectively, and the treatment efficacy, cardiac function index levels and quality of life were compared.
Results (1) After comparison, the clinical treatment efficacy of the experimental group was significantly higher, and the data were statistically significant (P < 0.05); (2) After treatment, the left ventricular end-diastolic diameter (LVEDD) and left ventricular end-systolic diameter (LVESD) of the experimental group were significantly lower than those of the reference group, and the left ventricular ejection fraction (LVEF) and cardiac output (CO) of the experimental group were significantly higher than those of the reference group, and the data were statistically significant (P < 0.05); (3) After treatment, the quality of life score of the experimental group was significantly higher than that of the reference group, and the data were statistically significant (P < 0.05).
Conclusion   The application of amiodarone in the treatment of emergency coronary heart disease with tachyarrhythmia has significant clinical effect, which can not only significantly improve the patient's cardiac function, but also significantly improve the patient's quality of life, and is worthy of promotion.