Analysis of the Effect and Detection Rate of Four Gastric Functions in Gastric Disease Screening
胃功能四项在胃部疾病筛查的效果及检出率分析

摘要

目的 探讨胃功能四项在胃部疾病筛查的效果及检出率。方法 回顾性分析2021.01~2023.12佛山市南海区公共卫生医院接诊的胃部不适患者150例的临床资料，以胃镜检查结果分为慢性浅表性胃炎（A组，89例）、慢性浅表性胃炎伴糜烂组（B组，53例）、慢性浅表性胃炎伴萎缩组（C组，8例）；另择取同时期的健康体检者50例为对照组，均实施胃功能四项检测，对比4组对象检查结果。结果 与对照组相比，A、B、C组PGⅡ均升高，PGR均下降（P＜0.05），但PGⅠ水平各组间无差异（P＞0.05）；与C组相比，B组的PGⅡ水平低，A组、B组的PGR水平高（P＜0.05）；4组受检者的血清HpIgG抗体阳性检出率对比差异明显（P＜0.05），C组患者的阳性检出率最高。结论 胃功能四项能够客观反映胃黏膜状态和功能，为临床治疗提供参考。

Abstract

Objective To explore the effectiveness and detection rate of the four gastric functions in screening for gastric diseases.
Methods A retrospective analysis was conducted on the clinical data of 150 patients with gastric discomfort admitted to Nanhai District Public Health Hospital in Foshan City from January 2021 to December 2023. The patients were divided into three groups based on gastroscopy results: chronic superficial gastritis (Group A, 89 cases), chronic superficial gastritis with erosion (Group B, 53 cases), and chronic superficial gastritis with atrophy (Group C, 8 cases); Another 50 healthy individuals who underwent physical examinations during the same period were selected as the control group, and all underwent four tests for gastric function. The results of the four groups of subjects were compared.
Results Compared with the control group, PG Ⅱ increased and PGR decreased in groups A, B, and C (P<0.05), but there was no significant difference in PG Ⅰ levels among the groups (P>0.05).; Compared with Group C, Group B had lower levels of PGII, while Groups A and B had higher levels of PGR (P<0.05); There was a significant difference in the positive detection rate of serum HpIgG antibodies among the four groups of subjects (P<0.05), with group C having the highest positive detection rate.
Conclusion   The four aspects of gastric function can objectively reflect the status and function of gastric mucosa, providing reference for clinical treatment.