The application effect of hydrochlorothiazide and irbesartan in elderly patients with primary hypertension
氢氯噻嗪与厄贝沙坦在老年原发性高血压患者中的应用效果

摘要

目的 分析氢氯噻嗪与厄贝沙坦治疗老年原发性高血压的效果。方法 66例老年原发性高血压患者取自本院在2022年1月-2023年1月期间，以随机数字表法为参考组和实验组，每组33例，其中前者行厄贝沙坦治疗，后者在此基础上采取氢氯噻嗪治疗，对比两组疗效。结果 治疗有效率对比显示，实验组显高（P＜0.05）。血压指标对比显示，治疗前两组对比差异小（P＞0.05）。治疗后实验组显低（P＜0.05）。不良反应发生率对比显示，实验组显低（P＜0.05）。结论 老年原发性高血压患者行氢氯噻嗪与厄贝沙坦治疗效果相比单一用药更好，可提高患者治疗有效率，改善血压指标，且安全性高。

Abstract

Objective: To analyze the efficacy of hydrochlorothiazide and irbesartan in the treatment of elderly primary hypertension. Method: 66 elderly patients with primary hypertension were selected from our hospital from January 2022 to January 2023. The random number table method was used as the reference group and experimental group, with 33 cases in each group. The former received treatment with irbesartan, while the latter received treatment with hydrochlorothiazide on this basis. The efficacy of the two groups was compared. Result: The comparison of treatment effectiveness showed that the experimental group was significantly higher (P<0.05). The comparison of blood pressure indicators showed that there was little difference between the two groups before treatment (P>0.05). After treatment, the experimental group showed a significant decrease (P<0.05). The incidence of adverse reactions was significantly lower in the experimental group (P<0.05).
Conclusion  : Hydrochlorothiazide is more effective than irbesartan alone in the treatment of elderly patients with primary hypertension. It can improve the treatment efficacy, improve blood pressure indicators, and has high safety.