摘要
目的 分析急性胰腺炎（AP）患者使用生大黄水胃注和灌肠的效果。方法 从2021年7月-2022年12月的AP患者中随机抽取120例，随机数字表法为对照组（生大黄水胃注+高位灌肠）和观察组（生大黄水胃注+渐插式灌肠），对比两组治疗效果。结果 观察组治疗效果指标、治疗有效率、治疗后炎性因子、淀粉酶水平、胃肠激素水平、腹内压值优于对照组（P＜0.05）。结论 AP患者使用生大黄水胃注和渐插式灌肠治疗效果更优。
关键词： 生大黄水胃注和灌肠；急性胰腺炎；炎性因子水平；淀粉酶水平
Abstract
Objective: To analyze the effects of gastric injection and enema with Shengda Huangshui in patients with acute pancreatitis (AP). Method: 120 patients with acute pancreatitis (AP) from July 2021 to December 2022 were randomly selected. The random number table method was used to compare the treatment effects between the control group (treated with Shengda Huangshui gastric injection+high position enema) and the observation group (treated with Shengda Huangshui gastric injection+gradual insertion enema). The results showed that the treatment efficacy indicators, treatment effectiveness rate, post treatment inflammatory factors, amylase levels, gastrointestinal hormone levels, and intra-abdominal pressure values of the observation group were better than those of the control group (P<0.05). Conclusion : The use of Shengda Huangshui gastric injection and gradual insertion enema for the treatment of AP patients is more effective.
Key words： Shengda Huangshui gastric injection and enema; Acute pancreatitis; Inflammatory factor levels; Starch enzyme level
参考文献 References
[1] 贾晓妮.生大黄灌肠对非重症急性胰腺炎患者炎性反应的影响[J].检验医学与临床,2020,17(18):2717-2719.
[2] 张绍敏,田光芳,余玉红,张渊智.生大黄灌肠用于急性胰腺炎治疗中的疗效及对炎性因子水平的影响[J].云南中医中药杂志,2021,42(1):51-53.
[3] 王晓艳,林容枝,彭媛,等.自拟方联合大黄灌肠治疗急性胆源性胰腺炎对患者胰腺外分泌功能和凝血功能的影响[J].四川中医,2022,40(2):96-98.
[4] 刘博.生长抑素与生大黄灌肠联合在重症急性胰腺炎中的临床治疗效果分析[J].黑龙江中医药,2022,51(3):25-27.
[5] 马柳一,刘倩倩,韩冬冬,周鹏程,高敏,田源,周小燕.大承气汤灌肠联合芒硝外敷对中重度急性胰腺炎早期肠内营养耐受性的影响[J].山东中医杂志,2022,41(04):401-407.
[6] 朱晶晶.中药保留灌肠联合芒硝外敷辅助治疗重症急性胰腺炎的疗效观察及对TNF-α、IL-6的影响[J].中国中医药科技，2022,29(2):242-243+349.
[7] 余芳芳.大黄灌肠联合早期鼻空肠营养支持治疗重症急性胰腺炎的临床价值[J].实用中西医结合临床,2021, 21(21):24-25+65.
[8] 孙德霞,徐玉龙,李超凤.大黄灌肠辅助分级式急诊护理对急性胰腺炎患者血清Hcy、MDA、SOD水平的影响[J].四川中医,2020,38(8):207-210.
[9] 李斌杰, 周晓芳, 黄自冲. 生大黄灌肠联合芒硝外敷辅助治疗急性胰腺炎的临床研究[J]. 湖北中医杂志, 2022, 44(4):13-16.
[10] 胡国霞. 生大黄胃管注入联合芒硝外敷在急性胰腺炎治疗中的疗效观察[J]. 内蒙古中医药, 2022, 41(6):89-90.
[11] 田光芳, 张渊智, 张绍敏. 生大黄保留灌肠治疗急性胰腺炎临床观察[J]. 光明中医, 2022, 37(20):3739-3743.