Research progress analysis of minocycline in the treatment of periodontitis
米诺环素治疗牙周炎研究进展分析

摘要

近年来，人们饮食习惯发生改变，口腔疾病发病率也明显增多，牙周炎发病率呈现增长趋势，易诱发多种并发症，对人们身心健康造成影响。临床治疗主要清洁和平整牙根、抑制牙周炎发展和复发、减少牙周组织损伤为目的，而在治疗方法上需要加以注重。牙周炎治疗主要以手术加以药物辅助治疗，实现有效清洁牙菌斑、结石、食物残渣等物质，抑制胶原酶活性，改善牙周组织炎性反应，逐渐实现抗炎效果，从而促进牙周组织再生。临床常见用药米诺环素具有抑制胶原酶活性、促进牙周组织再生的作用，在治疗牙周炎上具有重要效果。为进一步分析米诺环素治疗牙周炎的具体作用，本研究通过对牙周炎采用米诺环素治疗的研究进展进行综述，为相关人员提供临床参考。

Abstract

In recent years, people's eating habits have changed, the incidence rate of oral diseases has also increased significantly, and the incidence rate of periodontitis shows an increasing trend, which is easy to induce a variety of complications, affecting people's physical and mental health. Clinical treatment mainly aims to clean and straighten the root of teeth, inhibit the development and recurrence of periodontitis, and reduce periodontal tissue damage, but attention should be paid to treatment methods. The treatment of periodontitis mainly involves surgery combined with medication to effectively clean plaque, stones, food residues, and other substances, inhibit collagenase activity, improve inflammatory reactions in periodontal tissue, gradually achieve anti-inflammatory effects, and promote periodontal tissue regeneration. Minocycline, a commonly used clinical medication, has the effect of inhibiting collagenase activity and promoting periodontal tissue regeneration, and has important effects in the treatment of periodontitis. To further analyze the specific effects of minocycline in the treatment of periodontitis, this study reviews the research progress on the use of minocycline in the treatment of periodontitis, providing clinical reference for relevant personnel.