Study on the efficacy of escitalopram and venlafaxine in the treatment of patients with anxiety and depression
焦虑合并抑郁患者在其治疗中应用艾司西酞普兰与文拉法辛的效果研究

摘要

目的 以提高焦虑合并抑郁治疗水平为研究目标，在临床中分别应用艾司西酞普兰与文拉法辛，明确其对焦虑合并抑郁患者的影响。方法 以2023.01-12时间段中于院内接受诊疗的焦虑合并抑郁患者为分析对象，共计95例，对各个患者进行编号后采取随机抽取法设置成对照组（49例）、观察组（46例），分别以文拉法辛方案、艾司西酞普兰方案实施两组治疗干预，对干预情况进行分析。结果 相关指标方面，两组相比，观察组各项值更高（P<0.05）。心理健康状态方面，两组相比，观察组各项值更低（P<0.05）。结论 在临床中应用艾司西酞普兰方案，有利于改善血清5-羟色胺、多巴胺以及脑电图α波的频率和波幅等相关指标，促进患者心理健康。

Abstract

Objective: The purpose of this study is to improve the treatment level of anxiety combined with depression, and to apply escitalopram and venlafaxine separately in clinical practice to clarify their effects on patients with anxiety combined with depression. Method: A total of 95 patients with anxiety and depression who received diagnosis and treatment in the hospital during the period of January to December 2023 were selected as the analysis objects. After numbering each patient, a random selection method was used to set them as a control group (49 cases) and an observation group (46 cases). Two treatment interventions were implemented using the venlafaxine regimen and the escitalopram regimen, respectively, and the intervention situation was analyzed. In terms of related indicators, the observation group had higher values (P<0.05) compared to the control group. In terms of mental health status, the observation group had lower values in all aspects compared to the two groups (P<0.05).
Conclusion  : The application of escitalopram regimen in clinical practice is beneficial for improving related indicators such as serum serotonin, dopamine, and frequency and amplitude of EEG alpha waves, and promoting patients' mental health.