Application of chlorhexidine oral care solution with different concentrations in intensive care unit patients
不同浓度氯己定口腔护理液在重症监护室病人中的应用

摘要

目的 研究对重症监护室患者在其护理工作中应用实施不同浓度氯己定口腔护理液时所展现的实施效果与实施价值。方法 本次研究的病例数为84例，他们均来自于2022年12月-2023年12月期间我院收治护理的重症监护室患者，根据奇偶数随机原则将其平均分为四组，分别为生理盐水组、0.12%氯己定组、0.20%氯己定组及2.00%氯己定组，并对四组患者的口腔评分、口腔菌群阳性检出率及肺炎发生率进行评价分析。结果 经干预后，四组患者护理前后的OAG评分和包括克雷伯肺炎菌、金黄色葡萄球菌、溶血性链球菌、大肠埃希氏菌、铜绿假单胞菌及鲍曼不动杆菌在内的口腔菌群阳性检出率组间数值P＜0.05，说明存在对比意义。而四组患者的肺炎发生率则组间数值P>0.05，说明存在无对比意义。结论 对重症监护室患者在其护理工作中应用实施不同浓度氯己定口腔护理液均对重症监护室患者的口腔环境有积极的改善作用，并对肺炎的发生情况有一定的抑制作用，值得在临床上进行推广。

Abstract

Objective To study the effect and value of oral care solution with different concentrations of chlorhexidine in intensive care unit patients.
Methods A total of 84 patients were enrolled in this study, all of whom were from intensive care units in our hospital from December 2022 to December 2023. They were divided into four groups according to the odd and even random principle: normal saline group, 0.12% chlorhexidine group, 0.20% chlorhexidine group and 2.00% chlorhexidine group. Oral scores, positive detection rate of oral flora and incidence of pneumonia were evaluated and analyzed.
Results After intervention, the value of OAG score and positive detection rate of oral bacteria including Klebsiella pneumoniae, Staphylococcus aureus, hemolytic streptococcus, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii before and after care among the four groups was P < 0.05, indicating comparative significance. The incidence of pneumonia among the four groups was P>0.05, indicating that there was no comparative significance.
Conclusion   The application of different concentrations of chlorhexidine oral care solution in the nursing work of patients in intensive care unit has a positive effect on the improvement of the oral environment of patients in intensive care unit, and has a certain inhibitory effect on the occurrence of pneumonia, which is worthy of clinical promotion.