摘要
目的 探讨阻塞性睡眠呼吸暂停低通气综合征（OSAHS）对晚期妊娠肥胖孕妇的影响。方法 本研究为回顾性分析，对象为2020年03月至2021年03月在柳州市工人医院产检行OSAHS筛查的晚期妊娠肥胖孕妇58例。根据是否患有OSAHS，将参与者分为OSAHS组（25例）和无OSAHS组（33例）。通过便携式睡眠监测仪对所有孕妇进行筛查，诊断OSAHS，并记录临床特征及母儿妊娠结局。结果 OSAHS组中妊娠晚期肥胖孕妇的孕前体重指数显著高于无OSAHS组（P<0.05）。OSAHS孕妇在妊娠期高血压疾病、分娩时BMI、分娩孕周及新生儿出生体重方面，与无OSAHS组相比均有显著差异（P<0.05）。其他妊娠相关并发症如妊娠期糖尿病、早产等差异无统计学意义（P>0.05）。结论 OSAHS在晚期妊娠肥胖孕妇中较为常见，与多种不良妊娠结局相关。识别并管理孕期OSAHS可能对降低妊娠并发症风险、改善母儿健康结局具有重要意义。
关键词： 阻塞性睡眠呼吸暂停低通气综合征（OSAHS）；妊娠；肥胖；妊娠并发症；妊娠结局
Abstract
Objective To investigate the effects of obstructive sleep apnea hypopnea syndrome (OSAHS) on obese pregnant women in the third trimester. Methods This study was a retrospective analysis, and the subjects were 58 obese pregnant women in the third trimester who underwent OSAHS screening in the obstetrical examination of Liuzhou Workers Hospital from March 2020 to March 2021. Participants were divided into OSAHS group (25 cases) and OSAHS-free group (33 cases) according to whether they had OSAHS or not. All pregnant women were screened with portable sleep monitors to diagnose OSAHS, and clinical features and maternal and maternal pregnancy outcomes were recorded. Results The pre-pregnancy body mass index of obese pregnant women in the third trimester of pregnancy in OSAHS group was significantly higher than that in OSAHS group (P<0.05). There were significant differences in hypertensive diseases during pregnancy, BMI at delivery, gestational weeks and birth weight of newborns in OSAHS pregnant women compared with those without OSAHS (P<0.05). There was no significant difference in other pregnancy-related complications such as gestational diabetes mellitus and preterm birth (P>0.05). Conclusion OSAHS is common in obese pregnant women in the third trimester and is associated with a variety of adverse pregnancy outcomes. Identification and management of OSAHS during pregnancy may be of great significance in reducing the risk of pregnancy complications and improving maternal and infant health outcomes.
Key words： Obstructive sleep apnea hypopnea syndrome (OSAHS); Pregnancy; Obesity; Pregnancy complications; Pregnancy outcome
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