Effects of honey wet compress and enteral nutrition in comprehensive oral care on radiation oral mucositis
综合口腔护理蜂蜜湿敷及肠内营养对放射性口腔黏膜炎的影响

摘要

放射性口腔黏膜炎的发生发展是多种因素共同作用的结果[1]。头颈部放疗患者为放射性口腔黏膜炎的高发群体，超过80％患者在放化疗过程中出现放射性口腔黏膜炎[2]。目前医疗领域针对口腔黏膜炎已制定相应的评估、预防及护理标准[3]，在实际的放化疗治疗工作展开过程中，相关治疗措施的可实施性较低，无法满足放化疗治疗工作的需求。口腔护理是口腔状况以及症状管理的重要措施[4]。蜂蜜具有抗菌、抗炎、镇痛、抗氧化等效用，是放射性口腔黏膜炎治疗以及相关疼痛缓解的有效辅助方案[5]。肠内营养支持是患者营养状况维持以及改善的有效方案。在放化疗干预工作中，将上述两种方案联合进行应用，能够有效改善放化疗对于患者造成的损害，降低放射性口腔黏膜炎发病率，延缓放射性口腔黏膜炎进展。本次研究将以在我院就诊的80例口腔癌放化疗恶性肿瘤患者为例，尝试将蜂蜜湿敷融入综合口腔护理方案之中将其与肠内营养方案联合应用，探究该方案在放化疗过程中所产生的口腔黏膜炎发生和发展的作用。

Abstract

The occurrence and development of radioactive oral mucositis is the result of multiple factors [1]. Patients with head and neck radiotherapy have a high incidence of radioactive oral mucositis, and more than 80% of patients have radioactive oral mucositis during radiotherapy and chemotherapy [2]. At present, the medical field has formulated corresponding evaluation, prevention and nursing standards for oral mucositis [3]. In the actual process of radiotherapy and chemotherapy treatment, the implementation of relevant treatment measures is low, which cannot meet the needs of radiotherapy and chemotherapy treatment. Oral care is an important measure for the management of oral conditions and symptoms [4]. Honey has antibacterial, anti-inflammatory, analgesic and antioxidant effects, and is an effective auxiliary program for the treatment of radioactive oral mucositis and related pain relief [5]. Enteral nutrition support is an effective method to maintain and improve the nutritional status of patients. In the intervention work of radiotherapy and chemotherapy, the combined application of the above two schemes can effectively improve the damage caused by radiotherapy and chemotherapy to patients, reduce the incidence of radiation oral mucositis, and delay the progression of radiation oral mucositis. This study will take 80 patients with malignant tumors of oral cancer treated by radiotherapy and chemotherapy in our hospital as an example, and try to integrate honey wet compress into the comprehensive oral care program and combine it with enteral nutrition program, so as to explore the effect of this program on the occurrence and development of oral mucositis caused by radiotherapy and chemotherapy.