Open Access Article
International Journal of Clinical Research. 2024; 8: (4) ; 67-70 ; DOI: 10.12208/j.ijcr.20240152.
Observation on curative effect of Linggan Wuwei Jiangxin Decoction on chronic bronchitis
苓甘五味姜辛汤治疗慢性支气管炎的疗效观察
作者：
陈志国 *
衡东县中医医院 湖南衡阳
*通讯作者：
陈志国,单位：衡东县中医医院 湖南衡阳；
发布时间: 2024-04-28 总浏览量: 231
PDF 全文下载
引用本文
摘要
目的 观察慢性支气管炎治疗中苓甘五味姜辛汤的疗效。方法 回顾性选取2020年2月-2023年2月本院呼吸内科慢性支气管炎患者100例，依据用药方法分为盐酸氨溴索治疗基础上苓甘五味姜辛汤组（苓甘五味姜辛汤组）、盐酸氨溴索治疗组两组，各50例。统计分析两组中医症候积分、炎症指标、肺功能与血气分析指标、免疫功能、临床疗效、不良反应发生情况、症状消失时间。结果 苓甘五味姜辛汤组患者的咳嗽、痰量、啰音、畏寒积分及总积分、IL-6、CRP、WBC、FRC、PaCO2均低于盐酸氨溴索治疗组（P<0.05），RR、PEF、PaO2、IgA、IgG、IgM水平均高于盐酸氨溴索治疗组（P<0.05）。苓甘五味姜辛汤组患者的总有效率98.00%（49/50）高于盐酸氨溴索治疗组82.00%（41/50）（χ2=7.111，P<0.05）。苓甘五味姜辛汤组患者的不良反应发生率2.00%（1/50）低于盐酸氨溴索治疗组22.00%（11/50）（χ2=9.470，P<0.05）。苓甘五味姜辛汤组患者的咳痰、咳嗽、发热、啰音消失时间均短于盐酸氨溴索治疗组（P<0.05）。结论 慢性支气管炎治疗中苓甘五味姜辛汤的疗效显著。
关键词： 慢性支气管炎；苓甘五味姜辛汤；盐酸氨溴索；中医症候积分；炎症指标；肺功能与血气分析指标；免疫功能；不良反应
Abstract
Objective To observe the curative effect of Linggan Wuwei Jiangxin Decoction in the treatment of chronic bronchitis. Methods 100 patients with chronic bronchitis in the respiratory department of our hospital from February 2020 to February 2023 were retrospectively selected and divided into two groups based on ambroxol hydrochloride treatment Linggan Wuwei Jiangxin Tang group (Linggan Wuwei Jiangxin Tang group) and ambroxol hydrochloride treatment group, with 50 cases each. TCM syndrome score, inflammation index, lung function and blood gas analysis index, immune function, clinical efficacy, occurrence of adverse reactions and symptom disappearance time of the two groups were statistically analyzed. Results The levels of cough, phlegm volume, rales, cold fear score and total score, IL-6, CRP, WBC, FRC and PaCO2 in Linggan Wuwejiangxin Tang group were lower than those in ambroxol hydrochloride treatment group (P<0.05), and the levels of RR, PEF, PaO2, IgA, IgG and IgM were higher than those in ambroxol hydrochloride treatment group (P<0.05). The total effective rate of Linggan WuweiJiangxin Decoction group was 98.00% (49/50) higher than that of ambroxol hydrochloride group (82.00% (41/50) (χ2=7.111, P<0.05). The incidence of adverse reactions in Linggan Wuwei Jiangxin Decoction group was 2.00% (1/50) lower than that in ambroxol hydrochloride group (22.00% (11/50) (χ2=9.470, P<0.05). The disappearance time of sputum, cough, fever and rales in Linggan Wuwei Jiangxin Decoction group was shorter than that in ambroxol hydrochloride group (P<0.05). Conclusion Linggan Wuwei Jiangxin Decoction is effective in treating chronic bronchitis.
Key words： Chronic bronchitis; Linggan five-flavor ginger Xin Tang; Ambroxol hydrochloride; TCM syndrome score; Indicators of inflammation; Lung function and blood gas analysis index; Immune function; Adverse reaction
参考文献 References
[1] 蒋先伟,马战平. 苓甘五味姜辛汤治疗慢性支气管炎网络药理学研究[J]. 亚太传统医药,2021,17(8):175-180.
[2] 徐航,刘攀,戴小华. 苓甘五味姜辛汤治疗慢性支气管炎急性加重期(风寒袭肺证)的临床观察[J]. 中国中医急症,2022,31(7):1206-1209.
[3] 李镇宜. 苓甘五味姜辛汤联合左氧氟沙星治疗慢性支气管炎[J]. 深圳中西医结合杂志,2019,29(9):47-48.
[4] 郑瑜泓,袁世清. 苓甘五味姜辛汤对慢性支气管炎的作用机制[J]. 光明中医,2022,37(24):4477-4479.
[5] 段艳菊,牛喜平,谢亚丽. 苓甘五味姜辛汤加味联合穴位针刺治疗慢性支气管炎临床研究[J]. 亚太传统医药, 2021, 17(12):104-107.
[6] 李岩,李荣科,朱向东. 苓甘五味姜辛汤近5年研究进展[J]. 新中医,2015,47(10):212-213.
[7] 张永兵. 中西医结合治疗慢性支气管炎并发肺气肿的临床治疗效果分析[J]. 当代临床医刊,2020,33(3): 293, 266.
[8] 程飘芹,张碧海. 中医治疗慢性支气管炎的研究进展[J]. 中国民族民间医药,2023,32(14):78-82.
引用本文
陈志国, 苓甘五味姜辛汤治疗慢性支气管炎的疗效观察[J]. 国际临床研究杂志, 2024; 8: (4) : 67-70.