Analysis of influence of immunohistochemical staining on quality control of pathological techniques
免疫组化染色对病理技术质量控制的影响分析

摘要

目的 分析在病理技术质量控制中采取免疫组化染色所体现的效果。方法 将我院2022年7月至2023年7月这一时段内开展病理检查的患者纳入研究，入组对象共96例。并将所有患者随机进行随机组别划分，其中48例归入对照组，对其实施常规HE染色；另48例归入观察组，对其实施免疫组化染色。从切片质量、确诊情况、病理检验质量对两组作出综合评价。结果 观察组相较对照组，其切片质量优良率存在明显提高趋势，两组统计学有显著意义（P＜0.05）。观察组相较对照组，其确诊率存在更明显提高趋势，两组统计学有显著意义（P＜0.05）。观察组相较对照组，其取材质量、染色质量、试剂质量评分存在更明显升高趋势，两组统计学有显著意义（P＜0.05）。结论 临床病理检查中采取免疫组化染色可实现病理技术质量大幅提升，保证对疾病确诊率。

Abstract

Objective To analyze the effect of immunohistochemical staining on the quality control of pathological techniques.
Methods A total of 96 patients who underwent pathological examination in our hospital from July 2022 to July 2023 were included in the study. All patients were randomly divided into random groups, 48 of which were assigned to the control group, and routine HE staining was performed on them. Another 48 cases were assigned to the observation group, and immunohistochemical staining was performed on them. The two groups were evaluated comprehensively from the quality of section, diagnosis and pathological examination.
Results Compared with the control group, the section quality of the observation group had a more obvious trend of improvement, and the two groups had statistically significant significance (P < 0.05). Compared with the control group, the diagnosis rate of the observation group was more significantly increased, and there was statistically significant significance between the two groups (P < 0.05). Compared with the control group, the scores of sample quality, stain quality and reagent quality in the observation group were more significantly increased, with statistically significant significance between the two groups (P < 0.05).
Conclusion   Immunohistochemical staining in clinicopathological examination can greatly improve the quality of pathological techniques and ensure the diagnosis rate of diseases.