摘要
目的 分析慢性胃炎治疗中采取多潘立酮所体现的临床效果。方法 纳入我院2022年9月至2023年9月期间确诊医治的慢性胃炎患者，将全体96例患者随机划分两组，每组平均48例。对照组予雷尼替丁治疗，观察组予多潘立酮治疗。对两组患者临床治疗效果、炎症因子水平以及不良反应进行综合评价。结果 观察组总有效率较对照组提升更显著（P＜0.05）。观察组治疗后CRP、IL-32、MCP-1水平较对照组下降更显著（P＜0.05）。观察组不良反应发生率较对照组下降更显著（P＜0.05）。结论 慢性胃炎采取多潘立酮的疗效更显著，可缓解炎症反应，有良好安全性。
关键词： 慢性胃炎；多潘立酮；炎症反应
Abstract
Objective To analyze the clinical effect of domperidone in the treatment of chronic gastritis. Methods All 96 patients with chronic gastritis diagnosed and treated in our hospital from September 2022 to September 2023 were randomly divided into two groups, with an average of 48 cases in each group. The control group was treated with ranitidine and the observation group was treated with domperidone. The clinical therapeutic effect, inflammatory factor levels and adverse reactions of the two groups were comprehensively evaluated. Results The total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). The levels of CRP, IL-32 and MCP-1 in the observation group were significantly lower than those in the control group after treatment (P < 0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P < 0.05). Conclusion Domperidone is more effective in chronic gastritis, which can relieve inflammation and has good safety.
Key words： Chronic gastritis; Domperidone; Inflammatory response
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