Application study of early sustained low-dose dopamine pump infusion in the treatmentof critically ill newborns
早期持续小剂量多巴胺泵注在危重症新生儿治疗中的应用研究

摘要

目的 观察早期持续小剂量多巴胺泵注在危重症新生儿的治疗效果。方法 纳入2022年10月至2023年10月本院救治危重症新生儿，全部92例患儿随机分组，各组平均46例。对照组实施常规急救治疗，观察组在此基础上实施早期持续小剂量多巴胺泵注。评价危重症评分、并发症情况。结果 对比SNAP-Ⅱ、TRIPS评分，两组治疗后与同组治疗前对比均出现下降（P＜0.05）；同时观察指较对照组下降更明显（P＜0.05）。对比低钙血症、多系统器官衰竭情况，观察组其发生率与对照组比较下降更明显（P＜0.05）。结论 早期持续小剂量多巴胺泵注在危重症新生儿救治中能明显缓解病情，减少并发症出现。

Abstract

Objective To observe the therapeutic effect of early sustained low dose dopamine pumping in critically ill neonates.
Methods All 92 critically ill newborns treated in our hospital from October 2022 to October 2023 were randomly grouped, with an average of 46 cases in each group. The control group received routine emergency treatment, and the observation group received early sustained low-dose dopamine pumping on this basis. The critical illness score and complications were evaluated.
Results Compared with SNAP-Ⅱ and TRIPS scores, the scores of two groups after treatment were decreased compared with those before treatment (P < 0.05). At the same time, the observed index decreased significantly compared with the control group (P < 0.05). Compared with the control group, the incidence of hypocalcemia and multi-system organ failure decreased more significantly in the observation group (P < 0.05).
Conclusion   Early sustained low dose of dopamine pumping can significantly alleviate the condition and reduce the occurrence of complications in the treatment of critically ill newborns.