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Open Access Article

International Journal of Clinical Research. 2024; 8: (3) ; 21-29 ; DOI: 10.12208/j.ijcr.20240090.

Therapeutic advances in the use of Denosumab in pediatric orthopedic disorders
地舒单抗在儿童骨科疾病应用的治疗进展

作者: 蒙旭晗, 李川, 浦路桥, 卜鹏飞, 徐永清 *

中国人民解放军联勤保障部队第九二〇医院

*通讯作者: 徐永清,单位:中国人民解放军联勤保障部队第九二〇医院;

发布时间: 2024-03-26 总浏览量: 274

摘要

地舒单抗是治疗成年人骨骼疾病的一种有价值和安全的疗法,并已获得法规批准用于治疗骨质疏松症和骨转移。然而,由于缺乏高质量的儿童前瞻性研究,地舒单抗未被批准用于儿科。本综述旨在描述和讨论地舒单抗治疗儿童骨病的益处和缺点,并总结目前对地舒单抗在儿童中作用的认识。

关键词: 地舒单抗;儿童骨科疾病;治疗进展

Abstract

Denosumab is a valuable and safe treatment for skeletal diseases in adults, and has been approved by regulations for the treatment of osteoporosis and bone metastasis. However, due to the lack of high-quality prospective studies in children, denosumab has not been approved for pediatric use. This review aims to describe and discuss the benefits and disadvantages of denosumab in the treatment of bone diseases in children, and to summarize the current understanding of the role of denosumab in children.

Key words: Denosumab; Pediatric orthopedic disorders; Therapeutic advances

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引用本文

蒙旭晗, 李川, 浦路桥, 卜鹏飞, 徐永清, 地舒单抗在儿童骨科疾病应用的治疗进展[J]. 国际临床研究杂志, 2024; 8: (3) : 21-29.