Clinical analysis of colposcopy biopsy in the diagnosis of cervical diseases
阴道镜下活检诊断宫颈疾病临床效果分析

摘要

目的 讨论液基薄层细胞学检查与阴道镜检在妇科体检临床病理检验之中的效果。方法 选取时间在2020年1月-2021年1月在我科进行临床病理检查的1500例患者，探究液基薄层细胞学检查与阴道镜检的检出率。结果 通过对两组检出率进行对比可知，在检出宫颈炎疾病一项中阴道镜活检检出31例，占比15.5%，液基薄层细胞学检查32例，占比16.0.其中在浸润癌两组分别为32例（16.0%）、30例（15.0%）。宫颈息肉阴道镜活检检出32例，占比16.0%，液基薄层细胞学检查出29例，占比14.5%，上皮内瘤病变分别检出96例，占比48.0%。80例，40.0%。最终在检出率上，阴道镜活检为191例，占比95.5%，而液基薄层细胞学检查仅为85.5%。其中阴道镜活检方式误诊11例（42.5%）、漏诊9例（30.0%），诊断准确率为90.0%。液基薄层细胞学检查误诊19例（62.5%）、漏诊29例（32.5%），诊断准确率为76.0，阴道镜活检更优，P<0.05,差异具有统计学意义。结论 给予宫颈疾病患者采用阴道镜活检方式进行检查，可对患者病情进行良好检出，具有较高检出并以及诊断率，为临床治疗提供基础。

Abstract

Objective To discuss the effectiveness of liquid based thin layer cytology and colposcopy in clinical pathological examination of gynecological examination.
Methods 1500 patients who underwent clinical and pathological examinations in our department from January 2020 to January 2021 were selected to investigate the detection rate of liquid based thin layer cytology and colposcopy.
Results By comparing the detection rates between the two groups, it can be seen that in the detection of cervical inflammation disease, 31 cases were detected by colposcopy biopsy, accounting for 15.5%, and 32 cases were detected by liquid based thin layer cytology, accounting for 16.0%. Among them, 32 cases (16.0%) and 30 cases (15.0%) were detected in the invasive cancer groups, respectively. Cervical polyps were detected in 32 cases (16.0%) through colposcopy biopsy, 29 cases (14.5%) through liquid based thin layer cytology, and 96 cases (48.0%) through intraepithelial neoplasia. 80 cases, 40.0%. In terms of detection rate, there were 191 cases of colposcopy biopsy, accounting for 95.5%, while liquid based thin layer cytology examination was only 85.5%. Among them, 11 cases (42.5%) were misdiagnosed and 9 cases (30.0%) were misdiagnosed using colposcopy biopsy, with a diagnostic accuracy of 90.0%. 19 cases (62.5%) were misdiagnosed and 29 cases (32.5%) were missed in liquid based thin-layer cytology examination, with a diagnostic accuracy of 76.0. Vaginoscopy biopsy was better, P<0.05, and the difference was statistically significant.
Conclusion   The use of colposcopy biopsy for cervical disease patients can effectively detect their condition, have a high detection and diagnostic rate, and provide a foundation for clinical treatment.